SUMO-specific Isopeptidases Tuning Cardiac SUMOylation in Health and Disease
SUMOylation is a transient posttranslational modification with small-ubiquitin like modifiers (SUMO1, SUMO2 and SUMO3) covalently attached to their target-proteins via a multi-step enzymatic cascade. SUMOylation modifies protein-protein interactions, enzymatic-activity or chromatin binding in a mult...
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Main Authors: | Paul W. Hotz, Stefan Müller, Luca Mendler |
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Format: | article |
Language: | EN |
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Frontiers Media S.A.
2021
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Online Access: | https://doaj.org/article/7b7ed21fdeb5415085ef9e84f16dcc99 |
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