DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery

RNA-seq is a powerful tool to investigate how drugs affect the transcriptome but library construction can be costly. Here the authors introduce DRUG-seq, an automated platform for high-throughput transcriptome profiling.

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Autores principales:	Chaoyang Ye, Daniel J. Ho, Marilisa Neri, Chian Yang, Tripti Kulkarni, Ranjit Randhawa, Martin Henault, Nadezda Mostacci, Pierre Farmer, Steffen Renner, Robert Ihry, Leandra Mansur, Caroline Gubser Keller, Gregory McAllister, Marc Hild, Jeremy Jenkins, Ajamete Kaykas
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7b7edf1cccfe4d95aaa258f27cffc83f
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spelling	oai:doaj.org-article:7b7edf1cccfe4d95aaa258f27cffc83f2021-12-02T15:34:19ZDRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery10.1038/s41467-018-06500-x2041-1723https://doaj.org/article/7b7edf1cccfe4d95aaa258f27cffc83f2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06500-xhttps://doaj.org/toc/2041-1723RNA-seq is a powerful tool to investigate how drugs affect the transcriptome but library construction can be costly. Here the authors introduce DRUG-seq, an automated platform for high-throughput transcriptome profiling.Chaoyang YeDaniel J. HoMarilisa NeriChian YangTripti KulkarniRanjit RandhawaMartin HenaultNadezda MostacciPierre FarmerSteffen RennerRobert IhryLeandra MansurCaroline Gubser KellerGregory McAllisterMarc HildJeremy JenkinsAjamete KaykasNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chaoyang Ye Daniel J. Ho Marilisa Neri Chian Yang Tripti Kulkarni Ranjit Randhawa Martin Henault Nadezda Mostacci Pierre Farmer Steffen Renner Robert Ihry Leandra Mansur Caroline Gubser Keller Gregory McAllister Marc Hild Jeremy Jenkins Ajamete Kaykas DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery
description	RNA-seq is a powerful tool to investigate how drugs affect the transcriptome but library construction can be costly. Here the authors introduce DRUG-seq, an automated platform for high-throughput transcriptome profiling.
format	article
author	Chaoyang Ye Daniel J. Ho Marilisa Neri Chian Yang Tripti Kulkarni Ranjit Randhawa Martin Henault Nadezda Mostacci Pierre Farmer Steffen Renner Robert Ihry Leandra Mansur Caroline Gubser Keller Gregory McAllister Marc Hild Jeremy Jenkins Ajamete Kaykas
author_facet	Chaoyang Ye Daniel J. Ho Marilisa Neri Chian Yang Tripti Kulkarni Ranjit Randhawa Martin Henault Nadezda Mostacci Pierre Farmer Steffen Renner Robert Ihry Leandra Mansur Caroline Gubser Keller Gregory McAllister Marc Hild Jeremy Jenkins Ajamete Kaykas
author_sort	Chaoyang Ye
title	DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery
title_short	DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery
title_full	DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery
title_fullStr	DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery
title_full_unstemmed	DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery
title_sort	drug-seq for miniaturized high-throughput transcriptome profiling in drug discovery
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/7b7edf1cccfe4d95aaa258f27cffc83f
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DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery

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