Ingestion of BioCell Collagen®, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs

Ingestion of BioCell Collagen®, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs

Stephen R Schwartz,1 Joosang Park21International Research Services Inc, Port Chester, NY, USA; 2BioCell Technology, LLC, Newport Beach, CA, USAAbstract: Skin aging and its clinical manifestation is associated with altered molecular metabolism in the extracellular matrix of the dermis. In a pilot ope...

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Autores principales: Schwartz SR, Park J
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2012
Materias:
BioCell Collagen
chicken sternal cartilage extract
hydrolyzed collagen type II
low molecular weight hyaluronic acid
skin aging
Geriatrics
RC952-954.6
Acceso en línea:https://doaj.org/article/7b800da8547344bcaf71256d1e7a687f
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spelling oai:doaj.org-article:7b800da8547344bcaf71256d1e7a687f2021-12-02T03:45:53ZIngestion of BioCell Collagen®, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs1178-1998https://doaj.org/article/7b800da8547344bcaf71256d1e7a687f2012-07-01T00:00:00Zhttps://www.dovepress.com/ingestion-of-biocell-collagenreg-a-novel-hydrolyzed-chicken-sternal-ca-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Stephen R Schwartz,1 Joosang Park21International Research Services Inc, Port Chester, NY, USA; 2BioCell Technology, LLC, Newport Beach, CA, USAAbstract: Skin aging and its clinical manifestation is associated with altered molecular metabolism in the extracellular matrix of the dermis. In a pilot open-label study, we investigated the effect of a dietary supplement, BioCell Collagen® (BCC), which contains a naturally occurring matrix of hydrolyzed collagen type II and low-molecular-weight hyaluronic acid and chondroitin sulfate, in 26 healthy females who displayed visible signs of natural and photoaging in the face. Daily supplementation with 1 g of BCC for 12 weeks led to a significant reduction of skin dryness/scaling (76%, P = 0.002) and global lines/wrinkles (13.2%, P = 0.028) as measured by visual/tactile score. Additionally, a significant increase in the content of hemoglobin (17.7%, P = 0.018) and collagen (6.3%, P = 0.002) in the skin dermis was observed after 6 weeks of supplementation. At the end of the study, the increase in hemoglobin remained significant (15%, P = 0.008), while the increase in collagen content was maintained, but the difference from baseline was not significant (3.5%, P = 0.134). This study provides preliminary data suggesting that dietary supplementation with BCC elicits several physiological events which can be harnessed to counteract natural photoaging processes to reduce visible aging signs in the human face. A controlled study is necessary to verify these observations.Keywords: BioCell Collagen, chicken sternal cartilage extract, hydrolyzed collagen type II, low-molecular-weight hyaluronic acid, skin agingSchwartz SRPark JDove Medical PressarticleBioCell Collagenchicken sternal cartilage extracthydrolyzed collagen type IIlow molecular weight hyaluronic acidskin agingGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 7, Pp 267-273 (2012)
institution DOAJ
collection DOAJ
language EN
topic BioCell Collagen
chicken sternal cartilage extract
hydrolyzed collagen type II
low molecular weight hyaluronic acid
skin aging
Geriatrics
RC952-954.6
spellingShingle BioCell Collagen
chicken sternal cartilage extract
hydrolyzed collagen type II
low molecular weight hyaluronic acid
skin aging
Geriatrics
RC952-954.6
Schwartz SR
Park J
Ingestion of BioCell Collagen®, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs
description Stephen R Schwartz,1 Joosang Park21International Research Services Inc, Port Chester, NY, USA; 2BioCell Technology, LLC, Newport Beach, CA, USAAbstract: Skin aging and its clinical manifestation is associated with altered molecular metabolism in the extracellular matrix of the dermis. In a pilot open-label study, we investigated the effect of a dietary supplement, BioCell Collagen® (BCC), which contains a naturally occurring matrix of hydrolyzed collagen type II and low-molecular-weight hyaluronic acid and chondroitin sulfate, in 26 healthy females who displayed visible signs of natural and photoaging in the face. Daily supplementation with 1 g of BCC for 12 weeks led to a significant reduction of skin dryness/scaling (76%, P = 0.002) and global lines/wrinkles (13.2%, P = 0.028) as measured by visual/tactile score. Additionally, a significant increase in the content of hemoglobin (17.7%, P = 0.018) and collagen (6.3%, P = 0.002) in the skin dermis was observed after 6 weeks of supplementation. At the end of the study, the increase in hemoglobin remained significant (15%, P = 0.008), while the increase in collagen content was maintained, but the difference from baseline was not significant (3.5%, P = 0.134). This study provides preliminary data suggesting that dietary supplementation with BCC elicits several physiological events which can be harnessed to counteract natural photoaging processes to reduce visible aging signs in the human face. A controlled study is necessary to verify these observations.Keywords: BioCell Collagen, chicken sternal cartilage extract, hydrolyzed collagen type II, low-molecular-weight hyaluronic acid, skin aging
format article
author Schwartz SR
Park J
author_facet Schwartz SR
Park J
author_sort Schwartz SR
title Ingestion of BioCell Collagen®, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs
title_short Ingestion of BioCell Collagen®, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs
title_full Ingestion of BioCell Collagen®, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs
title_fullStr Ingestion of BioCell Collagen®, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs
title_full_unstemmed Ingestion of BioCell Collagen®, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs
title_sort ingestion of biocell collagen®, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs
publisher Dove Medical Press
publishDate 2012
url https://doaj.org/article/7b800da8547344bcaf71256d1e7a687f
work_keys_str_mv AT schwartzsr ingestionofbiocellcollagenreganovelhydrolyzedchickensternalcartilageextractenhancedbloodmicrocirculationandreducedfacialagingsigns
AT parkj ingestionofbiocellcollagenreganovelhydrolyzedchickensternalcartilageextractenhancedbloodmicrocirculationandreducedfacialagingsigns
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