Design of 3D Scaffolds for Hard Tissue Engineering: From Apatites to Silicon Mesoporous Materials

Advanced bioceramics for bone regeneration constitutes one of the pivotal interests in the multidisciplinary and far-sighted scientific trajectory of Prof. Vallet Regí. The different pathologies that affect osseous tissue substitution are considered to be one of the most important challenges from th...

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Autores principales:	Ana García, María Victoria Cabañas, Juan Peña, Sandra Sánchez-Salcedo
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	rapid prototyping GELPOR3D silica-hydroxyapatite mesoporous materials meso–macroporous scaffolds ceramic modifying agents Pharmacy and materia medica RS1-441
Acceso en línea:	https://doaj.org/article/7b81a5aebc3f494a91cdd2574fb72341
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id	oai:doaj.org-article:7b81a5aebc3f494a91cdd2574fb72341
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spelling	oai:doaj.org-article:7b81a5aebc3f494a91cdd2574fb723412021-11-25T18:42:47ZDesign of 3D Scaffolds for Hard Tissue Engineering: From Apatites to Silicon Mesoporous Materials10.3390/pharmaceutics131119811999-4923https://doaj.org/article/7b81a5aebc3f494a91cdd2574fb723412021-11-01T00:00:00Zhttps://www.mdpi.com/1999-4923/13/11/1981https://doaj.org/toc/1999-4923Advanced bioceramics for bone regeneration constitutes one of the pivotal interests in the multidisciplinary and far-sighted scientific trajectory of Prof. Vallet Regí. The different pathologies that affect osseous tissue substitution are considered to be one of the most important challenges from the health, social and economic point of view. 3D scaffolds based on bioceramics that mimic the composition, environment, microstructure and pore architecture of hard tissues is a consolidated response to such concerns. This review describes not only the different types of materials utilized: from apatite-type to silicon mesoporous materials, but also the fabrication techniques employed to design and adequate microstructure, a hierarchical porosity (from nano to macro scale), a cell-friendly surface; the inclusion of different type of biomolecules, drugs or cells within these scaffolds and the influence on their successful performance is thoughtfully reviewed.Ana GarcíaMaría Victoria CabañasJuan PeñaSandra Sánchez-SalcedoMDPI AGarticlerapid prototypingGELPOR3Dsilica-hydroxyapatitemesoporous materialsmeso–macroporous scaffoldsceramic modifying agentsPharmacy and materia medicaRS1-441ENPharmaceutics, Vol 13, Iss 1981, p 1981 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	rapid prototyping GELPOR3D silica-hydroxyapatite mesoporous materials meso–macroporous scaffolds ceramic modifying agents Pharmacy and materia medica RS1-441
spellingShingle	rapid prototyping GELPOR3D silica-hydroxyapatite mesoporous materials meso–macroporous scaffolds ceramic modifying agents Pharmacy and materia medica RS1-441 Ana García María Victoria Cabañas Juan Peña Sandra Sánchez-Salcedo Design of 3D Scaffolds for Hard Tissue Engineering: From Apatites to Silicon Mesoporous Materials
description	Advanced bioceramics for bone regeneration constitutes one of the pivotal interests in the multidisciplinary and far-sighted scientific trajectory of Prof. Vallet Regí. The different pathologies that affect osseous tissue substitution are considered to be one of the most important challenges from the health, social and economic point of view. 3D scaffolds based on bioceramics that mimic the composition, environment, microstructure and pore architecture of hard tissues is a consolidated response to such concerns. This review describes not only the different types of materials utilized: from apatite-type to silicon mesoporous materials, but also the fabrication techniques employed to design and adequate microstructure, a hierarchical porosity (from nano to macro scale), a cell-friendly surface; the inclusion of different type of biomolecules, drugs or cells within these scaffolds and the influence on their successful performance is thoughtfully reviewed.
format	article
author	Ana García María Victoria Cabañas Juan Peña Sandra Sánchez-Salcedo
author_facet	Ana García María Victoria Cabañas Juan Peña Sandra Sánchez-Salcedo
author_sort	Ana García
title	Design of 3D Scaffolds for Hard Tissue Engineering: From Apatites to Silicon Mesoporous Materials
title_short	Design of 3D Scaffolds for Hard Tissue Engineering: From Apatites to Silicon Mesoporous Materials
title_full	Design of 3D Scaffolds for Hard Tissue Engineering: From Apatites to Silicon Mesoporous Materials
title_fullStr	Design of 3D Scaffolds for Hard Tissue Engineering: From Apatites to Silicon Mesoporous Materials
title_full_unstemmed	Design of 3D Scaffolds for Hard Tissue Engineering: From Apatites to Silicon Mesoporous Materials
title_sort	design of 3d scaffolds for hard tissue engineering: from apatites to silicon mesoporous materials
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/7b81a5aebc3f494a91cdd2574fb72341
work_keys_str_mv	AT anagarcia designof3dscaffoldsforhardtissueengineeringfromapatitestosiliconmesoporousmaterials AT mariavictoriacabanas designof3dscaffoldsforhardtissueengineeringfromapatitestosiliconmesoporousmaterials AT juanpena designof3dscaffoldsforhardtissueengineeringfromapatitestosiliconmesoporousmaterials AT sandrasanchezsalcedo designof3dscaffoldsforhardtissueengineeringfromapatitestosiliconmesoporousmaterials
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Design of 3D Scaffolds for Hard Tissue Engineering: From Apatites to Silicon Mesoporous Materials

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