Structural Coupling between RNA Polymerase Composition and DNA Supercoiling in Coordinating Transcription: a Global Role for the Omega Subunit?
ABSTRACT In growing bacterial cells, the global reorganization of transcription is associated with alterations of RNA polymerase composition and the superhelical density of the DNA. However, the existence of any regulatory device coordinating these changes remains elusive. Here we show that in an ex...
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Autores principales: | Marcel Geertz, Andrew Travers, Sanja Mehandziska, Patrick Sobetzko, Sarath Chandra Janga, Nobuo Shimamoto, Georgi Muskhelishvili |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2011
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Acceso en línea: | https://doaj.org/article/7b8455f11d34455190918d449e0b0058 |
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