A multisystem inflammatory syndrome in children associated with COVID-19 in a 11-years-old girl

Introduction. Multisystem inflammatory syndrome in children (MIS-C) is a post-viral, life-threatening, inflammatory state with multisystem involvement that typically manifests 3–4 weeks after SARS-CoV-2 infection. In this article, we present the first case of MIS-C at the Institute for Child and You...

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Autores principales:	Bjelica Milena, Vilotijević-Dautović Gordana, Đuretić Andrea, Spasojević Slobodan
Formato:	article
Lenguaje:	EN SR
Publicado:	Serbian Medical Society 2021
Materias:	sars-cov-2 child inflammation immunoglobulins glucocorticoids Medicine R
Acceso en línea:	https://doaj.org/article/7b98393bc40d4c41b3b6ce4bb289be68
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spelling	oai:doaj.org-article:7b98393bc40d4c41b3b6ce4bb289be682021-11-10T07:28:10ZA multisystem inflammatory syndrome in children associated with COVID-19 in a 11-years-old girl0370-81792406-089510.2298/SARH210510078Bhttps://doaj.org/article/7b98393bc40d4c41b3b6ce4bb289be682021-01-01T00:00:00Zhttp://www.doiserbia.nb.rs/img/doi/0370-8179/2021/0370-81792100078B.pdfhttps://doaj.org/toc/0370-8179https://doaj.org/toc/2406-0895Introduction. Multisystem inflammatory syndrome in children (MIS-C) is a post-viral, life-threatening, inflammatory state with multisystem involvement that typically manifests 3–4 weeks after SARS-CoV-2 infection. In this article, we present the first case of MIS-C at the Institute for Child and Youth Health Care of Vojvodina at the beginning of the COVID-19 pandemic. Case outline. A previously healthy 11-year-old girl got sick two days before admission to the hospital with a fever, headache, vomiting, abdominal pain, and fatigue. She was tested positive for COVID-19 by a nasopharyngeal PCR swab with positive IgM and IgG antibodies. In the further course, the illness presented with prolonged fever, laboratory evidence of inflammation, multiorgan involvement such as respiratory, gastrointestinal, cardiovascular, and dermatologic. Based on CDC and WHO criteria, the diagnosis of MIS-C was made and IVIG and methylprednisolone were introduced with favorable clinical course. Conclusion. Every prolonged and unusual febrile state, especially if it is accompanied by gastrointestinal symptoms, in a school-age child, should be investigated in the direction of recent COVID-19 infection or exposure. In a case of a positive COVID-19 history or history of exposure, the MIS-C diagnosis should be considered.Bjelica MilenaVilotijević-Dautović GordanaĐuretić AndreaSpasojević SlobodanSerbian Medical Societyarticlesars-cov-2childinflammationimmunoglobulinsglucocorticoidsMedicineRENSRSrpski Arhiv za Celokupno Lekarstvo, Vol 149, Iss 9-10, Pp 604-608 (2021)
institution	DOAJ
collection	DOAJ
language	EN SR
topic	sars-cov-2 child inflammation immunoglobulins glucocorticoids Medicine R
spellingShingle	sars-cov-2 child inflammation immunoglobulins glucocorticoids Medicine R Bjelica Milena Vilotijević-Dautović Gordana Đuretić Andrea Spasojević Slobodan A multisystem inflammatory syndrome in children associated with COVID-19 in a 11-years-old girl
description	Introduction. Multisystem inflammatory syndrome in children (MIS-C) is a post-viral, life-threatening, inflammatory state with multisystem involvement that typically manifests 3–4 weeks after SARS-CoV-2 infection. In this article, we present the first case of MIS-C at the Institute for Child and Youth Health Care of Vojvodina at the beginning of the COVID-19 pandemic. Case outline. A previously healthy 11-year-old girl got sick two days before admission to the hospital with a fever, headache, vomiting, abdominal pain, and fatigue. She was tested positive for COVID-19 by a nasopharyngeal PCR swab with positive IgM and IgG antibodies. In the further course, the illness presented with prolonged fever, laboratory evidence of inflammation, multiorgan involvement such as respiratory, gastrointestinal, cardiovascular, and dermatologic. Based on CDC and WHO criteria, the diagnosis of MIS-C was made and IVIG and methylprednisolone were introduced with favorable clinical course. Conclusion. Every prolonged and unusual febrile state, especially if it is accompanied by gastrointestinal symptoms, in a school-age child, should be investigated in the direction of recent COVID-19 infection or exposure. In a case of a positive COVID-19 history or history of exposure, the MIS-C diagnosis should be considered.
format	article
author	Bjelica Milena Vilotijević-Dautović Gordana Đuretić Andrea Spasojević Slobodan
author_facet	Bjelica Milena Vilotijević-Dautović Gordana Đuretić Andrea Spasojević Slobodan
author_sort	Bjelica Milena
title	A multisystem inflammatory syndrome in children associated with COVID-19 in a 11-years-old girl
title_short	A multisystem inflammatory syndrome in children associated with COVID-19 in a 11-years-old girl
title_full	A multisystem inflammatory syndrome in children associated with COVID-19 in a 11-years-old girl
title_fullStr	A multisystem inflammatory syndrome in children associated with COVID-19 in a 11-years-old girl
title_full_unstemmed	A multisystem inflammatory syndrome in children associated with COVID-19 in a 11-years-old girl
title_sort	multisystem inflammatory syndrome in children associated with covid-19 in a 11-years-old girl
publisher	Serbian Medical Society
publishDate	2021
url	https://doaj.org/article/7b98393bc40d4c41b3b6ce4bb289be68
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A multisystem inflammatory syndrome in children associated with COVID-19 in a 11-years-old girl

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