Dataset of NMR-spectra pyrrolyl- and indolylazines and evidence of their ability to induce heat shock genes expression in human neurons

These data are related to our previous paper “Synthesis and approbation of new neuroprotective chemicals of pyrrolyl- and indolylazine classes in a cell model of Alzheimer's disease” (Dutysheva et al., 2021), in which we demonstrate neuroprotective abilities of pyrrolyl- and indolylazines in a...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Elizaveta A. Dutysheva, Irina A. Utepova, Maria A. Trestsova, Alexander S. Anisimov, Valery N. Charushin, Oleg N. Chupakhin, Boris A. Margulis, Irina V. Guzhova, Vladimir F. Lazarev
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Pyrrolylazines Indolylazines Photocatalysis Nuclear magnetic resonance Green chemistry Heat shock genes Computer applications to medicine. Medical informatics R858-859.7 Science (General) Q1-390
Acceso en línea:	https://doaj.org/article/7b9e6d3cd84847e3a178db7ff8b6c459
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:7b9e6d3cd84847e3a178db7ff8b6c459
record_format	dspace
spelling	oai:doaj.org-article:7b9e6d3cd84847e3a178db7ff8b6c4592021-11-18T04:49:18ZDataset of NMR-spectra pyrrolyl- and indolylazines and evidence of their ability to induce heat shock genes expression in human neurons2352-340910.1016/j.dib.2021.107562https://doaj.org/article/7b9e6d3cd84847e3a178db7ff8b6c4592021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2352340921008386https://doaj.org/toc/2352-3409These data are related to our previous paper “Synthesis and approbation of new neuroprotective chemicals of pyrrolyl- and indolylazine classes in a cell model of Alzheimer's disease” (Dutysheva et al., 2021), in which we demonstrate neuroprotective abilities of pyrrolyl- and indolylazines in a cell model of Alzheimer's disease. Using a novel procedure of photocatalysis we have synthesized a group of new compounds. The current article presents nuclear magnetic resonance spectra including heteronuclear single quantum coherence spectra of chemicals synthesized by us. The effect of new compounds have on heat shock proteins genes expression in reprogrammed human neurons are presented. We also presented data that verify neuronal phenotype of reprogrammed cells.Elizaveta A. DutyshevaIrina A. UtepovaMaria A. TrestsovaAlexander S. AnisimovValery N. CharushinOleg N. ChupakhinBoris A. MargulisIrina V. GuzhovaVladimir F. LazarevElsevierarticlePyrrolylazinesIndolylazinesPhotocatalysisNuclear magnetic resonanceGreen chemistryHeat shock genesComputer applications to medicine. Medical informaticsR858-859.7Science (General)Q1-390ENData in Brief, Vol 39, Iss , Pp 107562- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Pyrrolylazines Indolylazines Photocatalysis Nuclear magnetic resonance Green chemistry Heat shock genes Computer applications to medicine. Medical informatics R858-859.7 Science (General) Q1-390
spellingShingle	Pyrrolylazines Indolylazines Photocatalysis Nuclear magnetic resonance Green chemistry Heat shock genes Computer applications to medicine. Medical informatics R858-859.7 Science (General) Q1-390 Elizaveta A. Dutysheva Irina A. Utepova Maria A. Trestsova Alexander S. Anisimov Valery N. Charushin Oleg N. Chupakhin Boris A. Margulis Irina V. Guzhova Vladimir F. Lazarev Dataset of NMR-spectra pyrrolyl- and indolylazines and evidence of their ability to induce heat shock genes expression in human neurons
description	These data are related to our previous paper “Synthesis and approbation of new neuroprotective chemicals of pyrrolyl- and indolylazine classes in a cell model of Alzheimer's disease” (Dutysheva et al., 2021), in which we demonstrate neuroprotective abilities of pyrrolyl- and indolylazines in a cell model of Alzheimer's disease. Using a novel procedure of photocatalysis we have synthesized a group of new compounds. The current article presents nuclear magnetic resonance spectra including heteronuclear single quantum coherence spectra of chemicals synthesized by us. The effect of new compounds have on heat shock proteins genes expression in reprogrammed human neurons are presented. We also presented data that verify neuronal phenotype of reprogrammed cells.
format	article
author	Elizaveta A. Dutysheva Irina A. Utepova Maria A. Trestsova Alexander S. Anisimov Valery N. Charushin Oleg N. Chupakhin Boris A. Margulis Irina V. Guzhova Vladimir F. Lazarev
author_facet	Elizaveta A. Dutysheva Irina A. Utepova Maria A. Trestsova Alexander S. Anisimov Valery N. Charushin Oleg N. Chupakhin Boris A. Margulis Irina V. Guzhova Vladimir F. Lazarev
author_sort	Elizaveta A. Dutysheva
title	Dataset of NMR-spectra pyrrolyl- and indolylazines and evidence of their ability to induce heat shock genes expression in human neurons
title_short	Dataset of NMR-spectra pyrrolyl- and indolylazines and evidence of their ability to induce heat shock genes expression in human neurons
title_full	Dataset of NMR-spectra pyrrolyl- and indolylazines and evidence of their ability to induce heat shock genes expression in human neurons
title_fullStr	Dataset of NMR-spectra pyrrolyl- and indolylazines and evidence of their ability to induce heat shock genes expression in human neurons
title_full_unstemmed	Dataset of NMR-spectra pyrrolyl- and indolylazines and evidence of their ability to induce heat shock genes expression in human neurons
title_sort	dataset of nmr-spectra pyrrolyl- and indolylazines and evidence of their ability to induce heat shock genes expression in human neurons
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/7b9e6d3cd84847e3a178db7ff8b6c459
work_keys_str_mv	AT elizavetaadutysheva datasetofnmrspectrapyrrolylandindolylazinesandevidenceoftheirabilitytoinduceheatshockgenesexpressioninhumanneurons AT irinaautepova datasetofnmrspectrapyrrolylandindolylazinesandevidenceoftheirabilitytoinduceheatshockgenesexpressioninhumanneurons AT mariaatrestsova datasetofnmrspectrapyrrolylandindolylazinesandevidenceoftheirabilitytoinduceheatshockgenesexpressioninhumanneurons AT alexandersanisimov datasetofnmrspectrapyrrolylandindolylazinesandevidenceoftheirabilitytoinduceheatshockgenesexpressioninhumanneurons AT valeryncharushin datasetofnmrspectrapyrrolylandindolylazinesandevidenceoftheirabilitytoinduceheatshockgenesexpressioninhumanneurons AT olegnchupakhin datasetofnmrspectrapyrrolylandindolylazinesandevidenceoftheirabilitytoinduceheatshockgenesexpressioninhumanneurons AT borisamargulis datasetofnmrspectrapyrrolylandindolylazinesandevidenceoftheirabilitytoinduceheatshockgenesexpressioninhumanneurons AT irinavguzhova datasetofnmrspectrapyrrolylandindolylazinesandevidenceoftheirabilitytoinduceheatshockgenesexpressioninhumanneurons AT vladimirflazarev datasetofnmrspectrapyrrolylandindolylazinesandevidenceoftheirabilitytoinduceheatshockgenesexpressioninhumanneurons
_version_	1718425048668176384

Dataset of NMR-spectra pyrrolyl- and indolylazines and evidence of their ability to induce heat shock genes expression in human neurons

Ejemplares similares