Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice

Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice

Torpor is a state of reduced metabolism and body temperature that conserves energy when food is scarce. Here the authors show that estrogen-sensitive neurons in the hypothalamus regulate torpor in mice, maintaining torpor in both sexes but initiating torpor and regulating core temperature differenti...

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Auteurs principaux: Zhi Zhang, Fernando M. C. V. Reis, Yanlin He, Jae W. Park, Johnathon R. DiVittorio, Nilla Sivakumar, J. Edward van Veen, Sandra Maesta-Pereira, Michael Shum, India Nichols, Megan G. Massa, Shawn Anderson, Ketema Paul, Marc Liesa, Olujimi A. Ajijola, Yong Xu, Avishek Adhikari, Stephanie M. Correa
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Science
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Accès en ligne:https://doaj.org/article/7b9ecf04f1a846dda1413b72774ce3f8
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Résumé:Torpor is a state of reduced metabolism and body temperature that conserves energy when food is scarce. Here the authors show that estrogen-sensitive neurons in the hypothalamus regulate torpor in mice, maintaining torpor in both sexes but initiating torpor and regulating core temperature differentially across sex.

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