Circulating precursors of endothelial cells in patients with CHD and disturbed carbohydrate metabolism
Aim. Circulating precursors of endothelial cells (PEC) play an important role in regeneration of damaged vascular endothelium and myocardium and neovascularization of ischemic tissues. The aim of this work was to study effect of disturbed carbohydrate metabolism (DCM) on the number of PEC in patien...
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Endocrinology Research Centre
2010
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oai:doaj.org-article:7ba19c229e10493e990b5e2bb0fb51072021-11-14T09:00:14ZCirculating precursors of endothelial cells in patients with CHD and disturbed carbohydrate metabolism2072-03512072-037810.14341/2072-0351-6011https://doaj.org/article/7ba19c229e10493e990b5e2bb0fb51072010-03-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6011https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. Circulating precursors of endothelial cells (PEC) play an important role in regeneration of damaged vascular endothelium and myocardium and neovascularization of ischemic tissues. The aim of this work was to study effect of disturbed carbohydrate metabolism (DCM) on the number of PEC in patients with different forms of CHD. Materials and methods. The number of PEC was determined by flow cytofluometry, insulin and C-peptide levels by IFA in 78 patients aged 40-69 (mean 55.5?0.9) years. Control groups comprised 17 subjects without CHD and DCM, 33 patients were allocated to the stable angina (SA) group (48% with DCM), 28 suffered acute coronary syndrome without segment ST elevation (ACS-ST) (39% had DCM). Results. The number of PEC was reduced in all CHD patients, by 23% in the SA group (pMaria Mikhailovna RudaTatiana Igorevna Aref'evaAngelina Valer'evna SokolovaMarina Vladimirovna ShestakovaYury Alexandrovich KarpovElena Viktorovna ParfenovaEndocrinology Research Centrearticlecirculating precursors of endothelial cellsdisturbed carbohydrate metabolismcoronary heart diseaseNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 13, Iss 1, Pp 13-20 (2010) |
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circulating precursors of endothelial cells disturbed carbohydrate metabolism coronary heart disease Nutritional diseases. Deficiency diseases RC620-627 |
| spellingShingle |
circulating precursors of endothelial cells disturbed carbohydrate metabolism coronary heart disease Nutritional diseases. Deficiency diseases RC620-627 Maria Mikhailovna Ruda Tatiana Igorevna Aref'eva Angelina Valer'evna Sokolova Marina Vladimirovna Shestakova Yury Alexandrovich Karpov Elena Viktorovna Parfenova Circulating precursors of endothelial cells in patients with CHD and disturbed carbohydrate metabolism |
| description |
Aim. Circulating precursors of endothelial cells (PEC) play an important role in regeneration of damaged vascular endothelium and myocardium and neovascularization of ischemic tissues. The aim of this work was to study effect of disturbed carbohydrate metabolism (DCM) on the number of PEC in patients with different forms of CHD. Materials and methods. The number of PEC was determined by flow cytofluometry, insulin and C-peptide levels by IFA in 78 patients aged 40-69 (mean 55.5?0.9) years. Control groups comprised 17 subjects without CHD and DCM, 33 patients were allocated to the stable angina (SA) group (48% with DCM), 28 suffered acute coronary syndrome without segment ST elevation (ACS-ST) (39% had DCM). Results. The number of PEC was reduced in all CHD patients, by 23% in the SA group (p |
| format |
article |
| author |
Maria Mikhailovna Ruda Tatiana Igorevna Aref'eva Angelina Valer'evna Sokolova Marina Vladimirovna Shestakova Yury Alexandrovich Karpov Elena Viktorovna Parfenova |
| author_facet |
Maria Mikhailovna Ruda Tatiana Igorevna Aref'eva Angelina Valer'evna Sokolova Marina Vladimirovna Shestakova Yury Alexandrovich Karpov Elena Viktorovna Parfenova |
| author_sort |
Maria Mikhailovna Ruda |
| title |
Circulating precursors of endothelial cells in patients with CHD and disturbed carbohydrate metabolism |
| title_short |
Circulating precursors of endothelial cells in patients with CHD and disturbed carbohydrate metabolism |
| title_full |
Circulating precursors of endothelial cells in patients with CHD and disturbed carbohydrate metabolism |
| title_fullStr |
Circulating precursors of endothelial cells in patients with CHD and disturbed carbohydrate metabolism |
| title_full_unstemmed |
Circulating precursors of endothelial cells in patients with CHD and disturbed carbohydrate metabolism |
| title_sort |
circulating precursors of endothelial cells in patients with chd and disturbed carbohydrate metabolism |
| publisher |
Endocrinology Research Centre |
| publishDate |
2010 |
| url |
https://doaj.org/article/7ba19c229e10493e990b5e2bb0fb5107 |
| work_keys_str_mv |
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