A novel splice-site mutation in angiotensin I-converting enzyme (ACE) gene, c.3691+1G>A (IVS25+1G>A), causes a dramatic increase in circulating ACE through deletion of the transmembrane anchor.

A novel splice-site mutation in angiotensin I-converting enzyme (ACE) gene, c.3691+1G>A (IVS25+1G>A), causes a dramatic increase in circulating ACE through deletion of the transmembrane anchor.

<h4>Background</h4>Angiotensin-converting enzyme (ACE) (EC 4.15.1) metabolizes many biologically active peptides and plays a key role in blood pressure regulation and vascular remodeling. Elevated ACE levels are associated with different cardiovascular and respiratory diseases.<h4>...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Alexandre Persu, Michel Lambert, Jaap Deinum, Marta Cossu, Nathalie de Visscher, Leonid Irenge, Jerôme Ambroise, Jean-Marc Minon, Andrew B Nesterovitch, Alexander Churbanov, Isolda A Popova, Sergei M Danilov, A H Jan Danser, Jean-Luc Gala
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/7bae9c93159b40f4b827531676f729e2
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares