Dendritic cell MST1 inhibits Th17 differentiation

Dendritic cell MST1 inhibits Th17 differentiation

The differentiation of Th17 cells is central to infection and autoimmunity. Here, the authors show that expression of MST1 by dendritic cells limits IL-6 production and thereby controls Th17 differentiation in immunity to fungal infection and experimental autoimmune encephalomyelitis.

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Autores principales: Chunxiao Li, Yujing Bi, Yan Li, Hui Yang, Qing Yu, Jian Wang, Yu Wang, Huilin Su, Anna Jia, Ying Hu, Linian Han, Jiangyuan Zhang, Simin Li, Wufan Tao, Guangwei Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
Q
Acceso en línea:https://doaj.org/article/7bc77ada28784ea19eb14a65cc0d2d8b
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spelling oai:doaj.org-article:7bc77ada28784ea19eb14a65cc0d2d8b2021-12-02T14:42:18ZDendritic cell MST1 inhibits Th17 differentiation10.1038/ncomms142752041-1723https://doaj.org/article/7bc77ada28784ea19eb14a65cc0d2d8b2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14275https://doaj.org/toc/2041-1723The differentiation of Th17 cells is central to infection and autoimmunity. Here, the authors show that expression of MST1 by dendritic cells limits IL-6 production and thereby controls Th17 differentiation in immunity to fungal infection and experimental autoimmune encephalomyelitis.Chunxiao LiYujing BiYan LiHui YangQing YuJian WangYu WangHuilin SuAnna JiaYing HuLinian HanJiangyuan ZhangSimin LiWufan TaoGuangwei LiuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chunxiao Li
Yujing Bi
Yan Li
Hui Yang
Qing Yu
Jian Wang
Yu Wang
Huilin Su
Anna Jia
Ying Hu
Linian Han
Jiangyuan Zhang
Simin Li
Wufan Tao
Guangwei Liu
Dendritic cell MST1 inhibits Th17 differentiation
description The differentiation of Th17 cells is central to infection and autoimmunity. Here, the authors show that expression of MST1 by dendritic cells limits IL-6 production and thereby controls Th17 differentiation in immunity to fungal infection and experimental autoimmune encephalomyelitis.
format article
author Chunxiao Li
Yujing Bi
Yan Li
Hui Yang
Qing Yu
Jian Wang
Yu Wang
Huilin Su
Anna Jia
Ying Hu
Linian Han
Jiangyuan Zhang
Simin Li
Wufan Tao
Guangwei Liu
author_facet Chunxiao Li
Yujing Bi
Yan Li
Hui Yang
Qing Yu
Jian Wang
Yu Wang
Huilin Su
Anna Jia
Ying Hu
Linian Han
Jiangyuan Zhang
Simin Li
Wufan Tao
Guangwei Liu
author_sort Chunxiao Li
title Dendritic cell MST1 inhibits Th17 differentiation
title_short Dendritic cell MST1 inhibits Th17 differentiation
title_full Dendritic cell MST1 inhibits Th17 differentiation
title_fullStr Dendritic cell MST1 inhibits Th17 differentiation
title_full_unstemmed Dendritic cell MST1 inhibits Th17 differentiation
title_sort dendritic cell mst1 inhibits th17 differentiation
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/7bc77ada28784ea19eb14a65cc0d2d8b
work_keys_str_mv AT chunxiaoli dendriticcellmst1inhibitsth17differentiation
AT yujingbi dendriticcellmst1inhibitsth17differentiation
AT yanli dendriticcellmst1inhibitsth17differentiation
AT huiyang dendriticcellmst1inhibitsth17differentiation
AT qingyu dendriticcellmst1inhibitsth17differentiation
AT jianwang dendriticcellmst1inhibitsth17differentiation
AT yuwang dendriticcellmst1inhibitsth17differentiation
AT huilinsu dendriticcellmst1inhibitsth17differentiation
AT annajia dendriticcellmst1inhibitsth17differentiation
AT yinghu dendriticcellmst1inhibitsth17differentiation
AT linianhan dendriticcellmst1inhibitsth17differentiation
AT jiangyuanzhang dendriticcellmst1inhibitsth17differentiation
AT siminli dendriticcellmst1inhibitsth17differentiation
AT wufantao dendriticcellmst1inhibitsth17differentiation
AT guangweiliu dendriticcellmst1inhibitsth17differentiation
_version_ 1718389759456313344

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