Imunnological status in patients whis type 2 diabetes mellitus

Aim. To elucidate peculiarities of autorosette formation (ARF), immunological status and associated factors in patients with type 2 diabetes mellitus. Materials and methods. The study included 148 patients with DM2 and 63 practically healthy subjects. The following parameters were measured:the num...

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Autores principales:	Natalya Alexandrovna Belyakova, Evgenia Vladimirovna Rudenko, Daria Gennad'evna Mikhaylova, Elena Nikolaevna Egorova, Elizaveta Georgievna Nekrasova, Elena Dmitrievna Gogina
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2011
Materias:	type 2 diabetes mellitus immune status endogenous autorosette formation Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/7bcc82a0ed694c0c8d12e25022aff5bc
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spelling	oai:doaj.org-article:7bcc82a0ed694c0c8d12e25022aff5bc2021-11-14T09:00:16ZImunnological status in patients whis type 2 diabetes mellitus2072-03512072-037810.14341/2072-0351-5627https://doaj.org/article/7bcc82a0ed694c0c8d12e25022aff5bc2011-06-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5627https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To elucidate peculiarities of autorosette formation (ARF), immunological status and associated factors in patients with type 2 diabetes mellitus. Materials and methods. The study included 148 patients with DM2 and 63 practically healthy subjects. The following parameters were measured:the number of autorosettes in peripheral blood, C-reactive protein level, and humoral immunity (from blood immunoglobulin levels); spontaneousand induced TNB tests were performed. Results. Patients with DM2 suffered disturbances of carbohydrate metabolism and had an elevated number of autorosettes in peripheral blood, dysimmunoglobulinemia,increased level of acute phase protein, impaired functional activity of neutrophils. Conclusion. Intensity of ARF increases with duration of DM2 and a rise in AP. Patients with long-standing severe DM2, AH, micro- and macroalbuminurea,hyperglycemia, and triglyceridemia experience deterioration of immunological status.Natalya Alexandrovna BelyakovaEvgenia Vladimirovna RudenkoDaria Gennad'evna MikhaylovaElena Nikolaevna EgorovaElizaveta Georgievna NekrasovaElena Dmitrievna GoginaEndocrinology Research Centrearticletype 2 diabetes mellitusimmune statusendogenous autorosette formationNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 14, Iss 2, Pp 9-11 (2011)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	type 2 diabetes mellitus immune status endogenous autorosette formation Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	type 2 diabetes mellitus immune status endogenous autorosette formation Nutritional diseases. Deficiency diseases RC620-627 Natalya Alexandrovna Belyakova Evgenia Vladimirovna Rudenko Daria Gennad'evna Mikhaylova Elena Nikolaevna Egorova Elizaveta Georgievna Nekrasova Elena Dmitrievna Gogina Imunnological status in patients whis type 2 diabetes mellitus
description	Aim. To elucidate peculiarities of autorosette formation (ARF), immunological status and associated factors in patients with type 2 diabetes mellitus. Materials and methods. The study included 148 patients with DM2 and 63 practically healthy subjects. The following parameters were measured:the number of autorosettes in peripheral blood, C-reactive protein level, and humoral immunity (from blood immunoglobulin levels); spontaneousand induced TNB tests were performed. Results. Patients with DM2 suffered disturbances of carbohydrate metabolism and had an elevated number of autorosettes in peripheral blood, dysimmunoglobulinemia,increased level of acute phase protein, impaired functional activity of neutrophils. Conclusion. Intensity of ARF increases with duration of DM2 and a rise in AP. Patients with long-standing severe DM2, AH, micro- and macroalbuminurea,hyperglycemia, and triglyceridemia experience deterioration of immunological status.
format	article
author	Natalya Alexandrovna Belyakova Evgenia Vladimirovna Rudenko Daria Gennad'evna Mikhaylova Elena Nikolaevna Egorova Elizaveta Georgievna Nekrasova Elena Dmitrievna Gogina
author_facet	Natalya Alexandrovna Belyakova Evgenia Vladimirovna Rudenko Daria Gennad'evna Mikhaylova Elena Nikolaevna Egorova Elizaveta Georgievna Nekrasova Elena Dmitrievna Gogina
author_sort	Natalya Alexandrovna Belyakova
title	Imunnological status in patients whis type 2 diabetes mellitus
title_short	Imunnological status in patients whis type 2 diabetes mellitus
title_full	Imunnological status in patients whis type 2 diabetes mellitus
title_fullStr	Imunnological status in patients whis type 2 diabetes mellitus
title_full_unstemmed	Imunnological status in patients whis type 2 diabetes mellitus
title_sort	imunnological status in patients whis type 2 diabetes mellitus
publisher	Endocrinology Research Centre
publishDate	2011
url	https://doaj.org/article/7bcc82a0ed694c0c8d12e25022aff5bc
work_keys_str_mv	AT natalyaalexandrovnabelyakova imunnologicalstatusinpatientswhistype2diabetesmellitus AT evgeniavladimirovnarudenko imunnologicalstatusinpatientswhistype2diabetesmellitus AT dariagennadevnamikhaylova imunnologicalstatusinpatientswhistype2diabetesmellitus AT elenanikolaevnaegorova imunnologicalstatusinpatientswhistype2diabetesmellitus AT elizavetageorgievnanekrasova imunnologicalstatusinpatientswhistype2diabetesmellitus AT elenadmitrievnagogina imunnologicalstatusinpatientswhistype2diabetesmellitus
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Imunnological status in patients whis type 2 diabetes mellitus

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