Dual functional dinuclear platinum complex with selective reactivity towards c-myc G-quadruplex
Abstract G-quadruplexes (GQ) folded by the oncogenic G-rich sequences are the promising targets for developing anticancer therapeutic molecules. However, the current drug development mainly focused on non-covalent dynamic binders to stabilize GQ structures, while the covalent targeting from inorgani...
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Autores principales: | Lei He, Zhenyu Meng, Dechen Xu, Fangwei Shao |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/7bee6b42f63743659c0f684867f5e2be |
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