Hypoglycemia After Upper Gastrointestinal Surgery: Clinical Approach to Assessment, Diagnosis, and Treatment

Amanda Sheehan,1 Mary Elizabeth Patti1,2 1Research Division, Joslin Diabetes Center, Boston, MA, USA; 2Harvard Medical School, Boston, MA, USACorrespondence: Mary Elizabeth PattiResearch Division, Joslin Diabetes Center, 1 Joslin Place, Boston, MA 02215, USATel +1 617-309-1966Fax +1 617-309-2593Emai...

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Autores principales: Sheehan A, Patti ME
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spelling oai:doaj.org-article:7bee98d6acbe400a813deeb8006279ee2021-12-02T16:04:04ZHypoglycemia After Upper Gastrointestinal Surgery: Clinical Approach to Assessment, Diagnosis, and Treatment1178-7007https://doaj.org/article/7bee98d6acbe400a813deeb8006279ee2020-11-01T00:00:00Zhttps://www.dovepress.com/hypoglycemia-after-upper-gastrointestinal-surgery-clinical-approach-to-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Amanda Sheehan,1 Mary Elizabeth Patti1,2 1Research Division, Joslin Diabetes Center, Boston, MA, USA; 2Harvard Medical School, Boston, MA, USACorrespondence: Mary Elizabeth PattiResearch Division, Joslin Diabetes Center, 1 Joslin Place, Boston, MA 02215, USATel +1 617-309-1966Fax +1 617-309-2593Email Mary.elizabeth.patti@joslin.harvard.eduContext: Post-bariatric hypoglycemia (PBH) is an increasingly encountered complication of upper gastrointestinal surgery; the prevalence of this condition is anticipated to rise given yearly increases in bariatric surgical procedures. While PBH is incompletely understood, there is a growing body of research describing the associated factors, mechanisms, and treatment approaches for this condition.Evidence Acquisition: Data are integrated and summarized from studies of individuals affected by PBH and hypoglycemia following upper gastrointestinal surgery obtained from PubMed searches (1990– 2020).Evidence Synthesis: Information addressing etiology, incidence/prevalence, clinical characteristics, assessment, and treatment were reviewed and synthesized for the practicing physician. Literature reports were supplemented by clinical experience as indicated, when published data were not available.Conclusion: PBH can be life-altering and severe for a subset of individuals. Given the chronic nature of this condition, and sequelae of both acute and recurrent episodes, increasing provider awareness of both the condition and associated risk factors is critical for assessment, prompt diagnosis, treatment, and preoperative identification of individuals at risk.Keywords: hypoglycemia, post-bariatric hypoglycemia, upper gastrointestinal surgery, bariatric surgerySheehan APatti MEDove Medical Pressarticlehypoglycemiapost-bariatric hypoglycemiaupper gastrointestinal surgerybariatric surgerySpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 13, Pp 4469-4482 (2020)
institution DOAJ
collection DOAJ
language EN
topic hypoglycemia
post-bariatric hypoglycemia
upper gastrointestinal surgery
bariatric surgery
Specialties of internal medicine
RC581-951
spellingShingle hypoglycemia
post-bariatric hypoglycemia
upper gastrointestinal surgery
bariatric surgery
Specialties of internal medicine
RC581-951
Sheehan A
Patti ME
Hypoglycemia After Upper Gastrointestinal Surgery: Clinical Approach to Assessment, Diagnosis, and Treatment
description Amanda Sheehan,1 Mary Elizabeth Patti1,2 1Research Division, Joslin Diabetes Center, Boston, MA, USA; 2Harvard Medical School, Boston, MA, USACorrespondence: Mary Elizabeth PattiResearch Division, Joslin Diabetes Center, 1 Joslin Place, Boston, MA 02215, USATel +1 617-309-1966Fax +1 617-309-2593Email Mary.elizabeth.patti@joslin.harvard.eduContext: Post-bariatric hypoglycemia (PBH) is an increasingly encountered complication of upper gastrointestinal surgery; the prevalence of this condition is anticipated to rise given yearly increases in bariatric surgical procedures. While PBH is incompletely understood, there is a growing body of research describing the associated factors, mechanisms, and treatment approaches for this condition.Evidence Acquisition: Data are integrated and summarized from studies of individuals affected by PBH and hypoglycemia following upper gastrointestinal surgery obtained from PubMed searches (1990– 2020).Evidence Synthesis: Information addressing etiology, incidence/prevalence, clinical characteristics, assessment, and treatment were reviewed and synthesized for the practicing physician. Literature reports were supplemented by clinical experience as indicated, when published data were not available.Conclusion: PBH can be life-altering and severe for a subset of individuals. Given the chronic nature of this condition, and sequelae of both acute and recurrent episodes, increasing provider awareness of both the condition and associated risk factors is critical for assessment, prompt diagnosis, treatment, and preoperative identification of individuals at risk.Keywords: hypoglycemia, post-bariatric hypoglycemia, upper gastrointestinal surgery, bariatric surgery
format article
author Sheehan A
Patti ME
author_facet Sheehan A
Patti ME
author_sort Sheehan A
title Hypoglycemia After Upper Gastrointestinal Surgery: Clinical Approach to Assessment, Diagnosis, and Treatment
title_short Hypoglycemia After Upper Gastrointestinal Surgery: Clinical Approach to Assessment, Diagnosis, and Treatment
title_full Hypoglycemia After Upper Gastrointestinal Surgery: Clinical Approach to Assessment, Diagnosis, and Treatment
title_fullStr Hypoglycemia After Upper Gastrointestinal Surgery: Clinical Approach to Assessment, Diagnosis, and Treatment
title_full_unstemmed Hypoglycemia After Upper Gastrointestinal Surgery: Clinical Approach to Assessment, Diagnosis, and Treatment
title_sort hypoglycemia after upper gastrointestinal surgery: clinical approach to assessment, diagnosis, and treatment
publisher Dove Medical Press
publishDate 2020
url https://doaj.org/article/7bee98d6acbe400a813deeb8006279ee
work_keys_str_mv AT sheehana hypoglycemiaafteruppergastrointestinalsurgeryclinicalapproachtoassessmentdiagnosisandtreatment
AT pattime hypoglycemiaafteruppergastrointestinalsurgeryclinicalapproachtoassessmentdiagnosisandtreatment
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