Label-free spatio-temporal monitoring of cytosolic mass, osmolarity, and volume in living cells

Label-free, spatio-temporal imaging of cellular physiological responses is challenging. Here the authors combine digital holographic microscopy with a millifluidic chip and mathematical modelling to quantify cell volume, mass and cell uptake under changing environmental conditions.

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Détails bibliographiques
Auteurs principaux:	Daniel Midtvedt, Erik Olsén, Fredrik Höök, Gavin D. M. Jeffries
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2019
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/7beea7bfef8044bd83a66a1ec7e086bb
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id	oai:doaj.org-article:7beea7bfef8044bd83a66a1ec7e086bb
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spelling	oai:doaj.org-article:7beea7bfef8044bd83a66a1ec7e086bb2021-12-02T17:01:28ZLabel-free spatio-temporal monitoring of cytosolic mass, osmolarity, and volume in living cells10.1038/s41467-018-08207-52041-1723https://doaj.org/article/7beea7bfef8044bd83a66a1ec7e086bb2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08207-5https://doaj.org/toc/2041-1723Label-free, spatio-temporal imaging of cellular physiological responses is challenging. Here the authors combine digital holographic microscopy with a millifluidic chip and mathematical modelling to quantify cell volume, mass and cell uptake under changing environmental conditions.Daniel MidtvedtErik OlsénFredrik HöökGavin D. M. JeffriesNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Daniel Midtvedt Erik Olsén Fredrik Höök Gavin D. M. Jeffries Label-free spatio-temporal monitoring of cytosolic mass, osmolarity, and volume in living cells
description	Label-free, spatio-temporal imaging of cellular physiological responses is challenging. Here the authors combine digital holographic microscopy with a millifluidic chip and mathematical modelling to quantify cell volume, mass and cell uptake under changing environmental conditions.
format	article
author	Daniel Midtvedt Erik Olsén Fredrik Höök Gavin D. M. Jeffries
author_facet	Daniel Midtvedt Erik Olsén Fredrik Höök Gavin D. M. Jeffries
author_sort	Daniel Midtvedt
title	Label-free spatio-temporal monitoring of cytosolic mass, osmolarity, and volume in living cells
title_short	Label-free spatio-temporal monitoring of cytosolic mass, osmolarity, and volume in living cells
title_full	Label-free spatio-temporal monitoring of cytosolic mass, osmolarity, and volume in living cells
title_fullStr	Label-free spatio-temporal monitoring of cytosolic mass, osmolarity, and volume in living cells
title_full_unstemmed	Label-free spatio-temporal monitoring of cytosolic mass, osmolarity, and volume in living cells
title_sort	label-free spatio-temporal monitoring of cytosolic mass, osmolarity, and volume in living cells
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/7beea7bfef8044bd83a66a1ec7e086bb
work_keys_str_mv	AT danielmidtvedt labelfreespatiotemporalmonitoringofcytosolicmassosmolarityandvolumeinlivingcells AT erikolsen labelfreespatiotemporalmonitoringofcytosolicmassosmolarityandvolumeinlivingcells AT fredrikhook labelfreespatiotemporalmonitoringofcytosolicmassosmolarityandvolumeinlivingcells AT gavindmjeffries labelfreespatiotemporalmonitoringofcytosolicmassosmolarityandvolumeinlivingcells
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Label-free spatio-temporal monitoring of cytosolic mass, osmolarity, and volume in living cells

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