Label-free spatio-temporal monitoring of cytosolic mass, osmolarity, and volume in living cells
Label-free, spatio-temporal imaging of cellular physiological responses is challenging. Here the authors combine digital holographic microscopy with a millifluidic chip and mathematical modelling to quantify cell volume, mass and cell uptake under changing environmental conditions.
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Main Authors: | Daniel Midtvedt, Erik Olsén, Fredrik Höök, Gavin D. M. Jeffries |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
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Subjects: | |
Online Access: | https://doaj.org/article/7beea7bfef8044bd83a66a1ec7e086bb |
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