Mechanistic insight into bacterial entrapment by septin cage reconstitution

Septins are cytoskeletal proteins that assemble into complexes and contribute to immunity by entrapping intracellular bacteria in cage-like structures. Here, Lobato-Márquez et al. reconstitute septin cages in vitro using purified recombinant complexes, and study how these recognize bacterial cells a...

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Autores principales: Damián Lobato-Márquez, Jingwei Xu, Gizem Özbaykal Güler, Adaobi Ojiakor, Martin Pilhofer, Serge Mostowy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7bfe02646c054d8c8ec6e9ed6237ffa9
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spelling oai:doaj.org-article:7bfe02646c054d8c8ec6e9ed6237ffa92021-12-02T16:43:31ZMechanistic insight into bacterial entrapment by septin cage reconstitution10.1038/s41467-021-24721-52041-1723https://doaj.org/article/7bfe02646c054d8c8ec6e9ed6237ffa92021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24721-5https://doaj.org/toc/2041-1723Septins are cytoskeletal proteins that assemble into complexes and contribute to immunity by entrapping intracellular bacteria in cage-like structures. Here, Lobato-Márquez et al. reconstitute septin cages in vitro using purified recombinant complexes, and study how these recognize bacterial cells and assemble as filaments on their surface.Damián Lobato-MárquezJingwei XuGizem Özbaykal GülerAdaobi OjiakorMartin PilhoferSerge MostowyNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Damián Lobato-Márquez
Jingwei Xu
Gizem Özbaykal Güler
Adaobi Ojiakor
Martin Pilhofer
Serge Mostowy
Mechanistic insight into bacterial entrapment by septin cage reconstitution
description Septins are cytoskeletal proteins that assemble into complexes and contribute to immunity by entrapping intracellular bacteria in cage-like structures. Here, Lobato-Márquez et al. reconstitute septin cages in vitro using purified recombinant complexes, and study how these recognize bacterial cells and assemble as filaments on their surface.
format article
author Damián Lobato-Márquez
Jingwei Xu
Gizem Özbaykal Güler
Adaobi Ojiakor
Martin Pilhofer
Serge Mostowy
author_facet Damián Lobato-Márquez
Jingwei Xu
Gizem Özbaykal Güler
Adaobi Ojiakor
Martin Pilhofer
Serge Mostowy
author_sort Damián Lobato-Márquez
title Mechanistic insight into bacterial entrapment by septin cage reconstitution
title_short Mechanistic insight into bacterial entrapment by septin cage reconstitution
title_full Mechanistic insight into bacterial entrapment by septin cage reconstitution
title_fullStr Mechanistic insight into bacterial entrapment by septin cage reconstitution
title_full_unstemmed Mechanistic insight into bacterial entrapment by septin cage reconstitution
title_sort mechanistic insight into bacterial entrapment by septin cage reconstitution
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/7bfe02646c054d8c8ec6e9ed6237ffa9
work_keys_str_mv AT damianlobatomarquez mechanisticinsightintobacterialentrapmentbyseptincagereconstitution
AT jingweixu mechanisticinsightintobacterialentrapmentbyseptincagereconstitution
AT gizemozbaykalguler mechanisticinsightintobacterialentrapmentbyseptincagereconstitution
AT adaobiojiakor mechanisticinsightintobacterialentrapmentbyseptincagereconstitution
AT martinpilhofer mechanisticinsightintobacterialentrapmentbyseptincagereconstitution
AT sergemostowy mechanisticinsightintobacterialentrapmentbyseptincagereconstitution
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