Dermoscopy could be useful in differentiating sarcoidosis from necrobiotic granulomas even after treatment with systemic steroids

Background: Diagnosing cutaneous sarcoidosis and necrobiotic granulomas is challenging. Objective: Assessing the value of dermoscopy in differentiating cutaneous sarcoidosis from necrobiotic granulomas and evaluating whether their dermoscopic features will be altered after treatment. Meth...

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Autores principales:	Shahira Ramadan, Dalia Hossam, Marwah A. Saleh
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2016
Materias:	cutaneous sarcoidosis dermoscopy necrobiotic granuloma steroids treatment Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/7c01e194a4a94796ab5b1b3c67d464dc
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spelling	oai:doaj.org-article:7c01e194a4a94796ab5b1b3c67d464dc2021-11-17T08:31:13ZDermoscopy could be useful in differentiating sarcoidosis from necrobiotic granulomas even after treatment with systemic steroids10.5826/dpc.0603a052160-9381https://doaj.org/article/7c01e194a4a94796ab5b1b3c67d464dc2016-07-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/29https://doaj.org/toc/2160-9381 Background: Diagnosing cutaneous sarcoidosis and necrobiotic granulomas is challenging. Objective: Assessing the value of dermoscopy in differentiating cutaneous sarcoidosis from necrobiotic granulomas and evaluating whether their dermoscopic features will be altered after treatment. Methods: Nineteen cutaneous sarcoidosis and 11 necrobiotic granuloma patients (2 necrobiosis lipoidica, 4 granuloma annulare and 5 rheumatoid nodule) were included in this study. The diagnosis was confirmed by skin biopsy. The lesions were examined using non-contact polarized dermoscope (Dermlite 2 HR-Pro; 3Gen, San Juan Capistrano, CA). Results: Ten out of 19 cutaneous sarcoidosis patients and 7/11 necrobiotic cases group were receiving treatments (topical, intralesional or systemic steroids ± chloroquine) but still have cutaneous lesions. Treatment duration in the sarcoidosis group ranged from 2 months to 10 years (median 3 years) and in the necrobiotic cases group ranged from 3 months to 16 years (median 2 years). Pink homogenous background, translucent orange areas, white scar-like depigmentation and fine white scales were significantly associated with the cutaneous sarcoidosis compared to necrobiotic cases group. On the other hand mixed pink, white and yellowish background was significantly associated with the necrobiotic cases group. No significant difference in the dermoscopic findings was detected between treated and non-treated patients. Conclusion: Some dermoscopic findings are shared between the cutaneous sarcoidosis group and the necrobiotic cases group, yet dermoscopy could be a useful aid in differentiating them even after treatment. Shahira RamadanDalia HossamMarwah A. SalehMattioli1885articlecutaneous sarcoidosisdermoscopynecrobiotic granulomasteroidstreatmentDermatologyRL1-803ENDermatology Practical & Conceptual (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	cutaneous sarcoidosis dermoscopy necrobiotic granuloma steroids treatment Dermatology RL1-803
spellingShingle	cutaneous sarcoidosis dermoscopy necrobiotic granuloma steroids treatment Dermatology RL1-803 Shahira Ramadan Dalia Hossam Marwah A. Saleh Dermoscopy could be useful in differentiating sarcoidosis from necrobiotic granulomas even after treatment with systemic steroids
description	Background: Diagnosing cutaneous sarcoidosis and necrobiotic granulomas is challenging. Objective: Assessing the value of dermoscopy in differentiating cutaneous sarcoidosis from necrobiotic granulomas and evaluating whether their dermoscopic features will be altered after treatment. Methods: Nineteen cutaneous sarcoidosis and 11 necrobiotic granuloma patients (2 necrobiosis lipoidica, 4 granuloma annulare and 5 rheumatoid nodule) were included in this study. The diagnosis was confirmed by skin biopsy. The lesions were examined using non-contact polarized dermoscope (Dermlite 2 HR-Pro; 3Gen, San Juan Capistrano, CA). Results: Ten out of 19 cutaneous sarcoidosis patients and 7/11 necrobiotic cases group were receiving treatments (topical, intralesional or systemic steroids ± chloroquine) but still have cutaneous lesions. Treatment duration in the sarcoidosis group ranged from 2 months to 10 years (median 3 years) and in the necrobiotic cases group ranged from 3 months to 16 years (median 2 years). Pink homogenous background, translucent orange areas, white scar-like depigmentation and fine white scales were significantly associated with the cutaneous sarcoidosis compared to necrobiotic cases group. On the other hand mixed pink, white and yellowish background was significantly associated with the necrobiotic cases group. No significant difference in the dermoscopic findings was detected between treated and non-treated patients. Conclusion: Some dermoscopic findings are shared between the cutaneous sarcoidosis group and the necrobiotic cases group, yet dermoscopy could be a useful aid in differentiating them even after treatment.
format	article
author	Shahira Ramadan Dalia Hossam Marwah A. Saleh
author_facet	Shahira Ramadan Dalia Hossam Marwah A. Saleh
author_sort	Shahira Ramadan
title	Dermoscopy could be useful in differentiating sarcoidosis from necrobiotic granulomas even after treatment with systemic steroids
title_short	Dermoscopy could be useful in differentiating sarcoidosis from necrobiotic granulomas even after treatment with systemic steroids
title_full	Dermoscopy could be useful in differentiating sarcoidosis from necrobiotic granulomas even after treatment with systemic steroids
title_fullStr	Dermoscopy could be useful in differentiating sarcoidosis from necrobiotic granulomas even after treatment with systemic steroids
title_full_unstemmed	Dermoscopy could be useful in differentiating sarcoidosis from necrobiotic granulomas even after treatment with systemic steroids
title_sort	dermoscopy could be useful in differentiating sarcoidosis from necrobiotic granulomas even after treatment with systemic steroids
publisher	Mattioli1885
publishDate	2016
url	https://doaj.org/article/7c01e194a4a94796ab5b1b3c67d464dc
work_keys_str_mv	AT shahiraramadan dermoscopycouldbeusefulindifferentiatingsarcoidosisfromnecrobioticgranulomasevenaftertreatmentwithsystemicsteroids AT daliahossam dermoscopycouldbeusefulindifferentiatingsarcoidosisfromnecrobioticgranulomasevenaftertreatmentwithsystemicsteroids AT marwahasaleh dermoscopycouldbeusefulindifferentiatingsarcoidosisfromnecrobioticgranulomasevenaftertreatmentwithsystemicsteroids
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Dermoscopy could be useful in differentiating sarcoidosis from necrobiotic granulomas even after treatment with systemic steroids

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