Block characteristics of Dexmedetomidine as an adjuvant to local anaesthetic in Infraclavicular brachial plexus block using peripheral nerve stimulator and ultrasound

Introduction: Dexmedetomidine has been frequently used in regional anaesthesia to improve the quality of blocks. Addition of dexmedetomidine to local anaesthetics has been shown to hasten the onset of both sensory and motor blocks and also prolong the duration of analgesia. The objective of this pr...

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Autores principales: Ujma Shrestha, Sushila Lama Moktan, Sanjay Shrestha
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Publicado: Society of Surgeons of Nepal 2021
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spelling oai:doaj.org-article:7c05fa46cc3642e088352818839426592021-12-05T19:15:35ZBlock characteristics of Dexmedetomidine as an adjuvant to local anaesthetic in Infraclavicular brachial plexus block using peripheral nerve stimulator and ultrasound10.3126/jssn.v23i2.358331815-39842392-4772https://doaj.org/article/7c05fa46cc3642e088352818839426592021-03-01T00:00:00Zhttps://www.nepjol.info/index.php/JSSN/article/view/35833https://doaj.org/toc/1815-3984https://doaj.org/toc/2392-4772 Introduction: Dexmedetomidine has been frequently used in regional anaesthesia to improve the quality of blocks. Addition of dexmedetomidine to local anaesthetics has been shown to hasten the onset of both sensory and motor blocks and also prolong the duration of analgesia. The objective of this prospective comparative study was to assess the change in characteristics of infraclavicular brachial plexus block after adding Inj. Dexmedetomidine to 2% Lignocaine with Adrenaline. Methods: Sixty-six patients, scheduled for upper limb surgeries under ultrasound guided infraclavicular brachial plexus block were randomly allocated to two groups. Group LS received Inj. Lignocaine 2% with Adrenaline, 7mg/kg diluted to 30 ml with saline and Group LD received Inj. Dexmedetomidine 0.75 mcg/kg in addition to Inj. Lignocaine 2% with Adrenaline, 7mg/kg again diluted to a total volume of 30 ml. The parameters studied were: onset of sensory and motor blocks and duration of analgesia. Results: Sixty patients completed the study. The demographic variables and motor block were similar between both groups. The mean time to onset of sensory block was significantly faster in Group LD compared to Group LS (9.80±4.85 min vs 12.30±3.97 min, p=0.033). The duration of analgesia was also found to be prolonged in Group LD compared to Group LS (286.73±55.38 min vs 226.53±41.19 min, p < 0.001). Conclusion: Addition of 0.75 mcg/kg of Dexmedetomidine to 2% Lignocaine with Adrenaline hastens the onset of sensory block and prolongs the duration of analgesia in ultrasound guided and peripheral nerve stimulator guided infraclavicular block. Ujma ShresthaSushila Lama MoktanSanjay ShresthaSociety of Surgeons of Nepalarticleanalgesiadexmedetomidineinfraclavicular plexus blocklignocainesensory blockSurgeryRD1-811ENJournal of Society of Surgeons of Nepal, Vol 23, Iss 2 (2021)
institution DOAJ
collection DOAJ
language EN
topic analgesia
dexmedetomidine
infraclavicular plexus block
lignocaine
sensory block
Surgery
RD1-811
spellingShingle analgesia
dexmedetomidine
infraclavicular plexus block
lignocaine
sensory block
Surgery
RD1-811
Ujma Shrestha
Sushila Lama Moktan
Sanjay Shrestha
Block characteristics of Dexmedetomidine as an adjuvant to local anaesthetic in Infraclavicular brachial plexus block using peripheral nerve stimulator and ultrasound
description Introduction: Dexmedetomidine has been frequently used in regional anaesthesia to improve the quality of blocks. Addition of dexmedetomidine to local anaesthetics has been shown to hasten the onset of both sensory and motor blocks and also prolong the duration of analgesia. The objective of this prospective comparative study was to assess the change in characteristics of infraclavicular brachial plexus block after adding Inj. Dexmedetomidine to 2% Lignocaine with Adrenaline. Methods: Sixty-six patients, scheduled for upper limb surgeries under ultrasound guided infraclavicular brachial plexus block were randomly allocated to two groups. Group LS received Inj. Lignocaine 2% with Adrenaline, 7mg/kg diluted to 30 ml with saline and Group LD received Inj. Dexmedetomidine 0.75 mcg/kg in addition to Inj. Lignocaine 2% with Adrenaline, 7mg/kg again diluted to a total volume of 30 ml. The parameters studied were: onset of sensory and motor blocks and duration of analgesia. Results: Sixty patients completed the study. The demographic variables and motor block were similar between both groups. The mean time to onset of sensory block was significantly faster in Group LD compared to Group LS (9.80±4.85 min vs 12.30±3.97 min, p=0.033). The duration of analgesia was also found to be prolonged in Group LD compared to Group LS (286.73±55.38 min vs 226.53±41.19 min, p < 0.001). Conclusion: Addition of 0.75 mcg/kg of Dexmedetomidine to 2% Lignocaine with Adrenaline hastens the onset of sensory block and prolongs the duration of analgesia in ultrasound guided and peripheral nerve stimulator guided infraclavicular block.
format article
author Ujma Shrestha
Sushila Lama Moktan
Sanjay Shrestha
author_facet Ujma Shrestha
Sushila Lama Moktan
Sanjay Shrestha
author_sort Ujma Shrestha
title Block characteristics of Dexmedetomidine as an adjuvant to local anaesthetic in Infraclavicular brachial plexus block using peripheral nerve stimulator and ultrasound
title_short Block characteristics of Dexmedetomidine as an adjuvant to local anaesthetic in Infraclavicular brachial plexus block using peripheral nerve stimulator and ultrasound
title_full Block characteristics of Dexmedetomidine as an adjuvant to local anaesthetic in Infraclavicular brachial plexus block using peripheral nerve stimulator and ultrasound
title_fullStr Block characteristics of Dexmedetomidine as an adjuvant to local anaesthetic in Infraclavicular brachial plexus block using peripheral nerve stimulator and ultrasound
title_full_unstemmed Block characteristics of Dexmedetomidine as an adjuvant to local anaesthetic in Infraclavicular brachial plexus block using peripheral nerve stimulator and ultrasound
title_sort block characteristics of dexmedetomidine as an adjuvant to local anaesthetic in infraclavicular brachial plexus block using peripheral nerve stimulator and ultrasound
publisher Society of Surgeons of Nepal
publishDate 2021
url https://doaj.org/article/7c05fa46cc3642e08835281883942659
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AT sushilalamamoktan blockcharacteristicsofdexmedetomidineasanadjuvanttolocalanaestheticininfraclavicularbrachialplexusblockusingperipheralnervestimulatorandultrasound
AT sanjayshrestha blockcharacteristicsofdexmedetomidineasanadjuvanttolocalanaestheticininfraclavicularbrachialplexusblockusingperipheralnervestimulatorandultrasound
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