Association Between Sarcopenia and Depressive Symptoms in Chinese Older Adults: Evidence From the China Health and Retirement Longitudinal Study

Background: Little is known about whether sarcopenia predicts incident depressive symptoms in older adults. Using the nationally representative data from the China Health and Retirement Longitudinal Study (CHARLS), we conducted cross-sectional and longitudinal analyses to estimate the association be...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ke Gao, Wen-Zhuo Ma, Scarlett Huck, Bo-Lin Li, Li Zhang, Jiao Zhu, Tian Li, Dan Zhou
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	sarcopenia possible sarcopenia depressive symptoms low muscle mass older adults Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/7c12b435113c4db3bd6523b0c9311105
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:7c12b435113c4db3bd6523b0c9311105
record_format	dspace
spelling	oai:doaj.org-article:7c12b435113c4db3bd6523b0c93111052021-11-17T05:21:58ZAssociation Between Sarcopenia and Depressive Symptoms in Chinese Older Adults: Evidence From the China Health and Retirement Longitudinal Study2296-858X10.3389/fmed.2021.755705https://doaj.org/article/7c12b435113c4db3bd6523b0c93111052021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fmed.2021.755705/fullhttps://doaj.org/toc/2296-858XBackground: Little is known about whether sarcopenia predicts incident depressive symptoms in older adults. Using the nationally representative data from the China Health and Retirement Longitudinal Study (CHARLS), we conducted cross-sectional and longitudinal analyses to estimate the association between sarcopenia and depressive symptoms among older adults.Methods: The sample comprised 7,706 participants aged at least 60 years (50.6% women; mean age 68.0 ± 6.5) from the CHARLS 2015. Based on the Asian Working Group for Sarcopenia 2019 (AWGS 2019) criteria, sarcopenia status was classified into three types: no-sarcopenia, possible sarcopenia, and sarcopenia. Depressive symptoms were assessed using the validated 10-items of the Center for Epidemiologic Studies Depression Scale. A cross-sectional analysis was used to examine the relationship between sarcopenia status and depressive symptoms. A total of 4,652 participants without depressive symptoms were recruited from the same cohort in 2015 and were followed up in 2018. Cox proportional hazards regression models were conducted to examine the effect of sarcopenia status on subsequent depressive symptoms with the report of hazard ratio (HR).Results: The prevalence of depressive symptoms in total populations, no-sarcopenia, possible sarcopenia, and sarcopenia individuals were 27.1% (2085/7706), 21.5% (927/4310), 33.6% (882/2627), and 35.9% (276/769), respectively. Both possible sarcopenia (OR: 1.75, 95% CI: 1.46–2.10) and sarcopenia (OR: 1.64, 95% CI: 1.23–2.19) were positively associated with higher odds of depressive symptoms (all p < 0.01). During the 3.7 years of follow-up, 956 cases (20.6%) with incident depressive symptoms were identified. In the longitudinal analysis, individuals with the diagnosed possible sarcopenia (HR: 1.27, 95% CI: 1.01–1.58) and sarcopenia participants (HR: 1.49, 95% CI: 1.06–2.09) were more likely to have new onset depressive symptoms than no-sarcopenia peers.Conclusions: Both possible sarcopenia and sarcopenia, assessed using the AWGS 2019 criteria, were independent predictors for the occurrence of depressive symptoms among Chinese older adults. Our findings provided new evidence supporting the longitudinal connection between sarcopenia and mental health problems, it also provides further justification for timely identification and management of both possible sarcopenia and sarcopenia as part of comprehensive strategies to fight against depressive symptoms.Ke GaoWen-Zhuo MaWen-Zhuo MaScarlett HuckBo-Lin LiLi ZhangJiao ZhuTian LiDan ZhouFrontiers Media S.A.articlesarcopeniapossible sarcopeniadepressive symptomslow muscle massolder adultsMedicine (General)R5-920ENFrontiers in Medicine, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	sarcopenia possible sarcopenia depressive symptoms low muscle mass older adults Medicine (General) R5-920
spellingShingle	sarcopenia possible sarcopenia depressive symptoms low muscle mass older adults Medicine (General) R5-920 Ke Gao Wen-Zhuo Ma Wen-Zhuo Ma Scarlett Huck Bo-Lin Li Li Zhang Jiao Zhu Tian Li Dan Zhou Association Between Sarcopenia and Depressive Symptoms in Chinese Older Adults: Evidence From the China Health and Retirement Longitudinal Study
description	Background: Little is known about whether sarcopenia predicts incident depressive symptoms in older adults. Using the nationally representative data from the China Health and Retirement Longitudinal Study (CHARLS), we conducted cross-sectional and longitudinal analyses to estimate the association between sarcopenia and depressive symptoms among older adults.Methods: The sample comprised 7,706 participants aged at least 60 years (50.6% women; mean age 68.0 ± 6.5) from the CHARLS 2015. Based on the Asian Working Group for Sarcopenia 2019 (AWGS 2019) criteria, sarcopenia status was classified into three types: no-sarcopenia, possible sarcopenia, and sarcopenia. Depressive symptoms were assessed using the validated 10-items of the Center for Epidemiologic Studies Depression Scale. A cross-sectional analysis was used to examine the relationship between sarcopenia status and depressive symptoms. A total of 4,652 participants without depressive symptoms were recruited from the same cohort in 2015 and were followed up in 2018. Cox proportional hazards regression models were conducted to examine the effect of sarcopenia status on subsequent depressive symptoms with the report of hazard ratio (HR).Results: The prevalence of depressive symptoms in total populations, no-sarcopenia, possible sarcopenia, and sarcopenia individuals were 27.1% (2085/7706), 21.5% (927/4310), 33.6% (882/2627), and 35.9% (276/769), respectively. Both possible sarcopenia (OR: 1.75, 95% CI: 1.46–2.10) and sarcopenia (OR: 1.64, 95% CI: 1.23–2.19) were positively associated with higher odds of depressive symptoms (all p < 0.01). During the 3.7 years of follow-up, 956 cases (20.6%) with incident depressive symptoms were identified. In the longitudinal analysis, individuals with the diagnosed possible sarcopenia (HR: 1.27, 95% CI: 1.01–1.58) and sarcopenia participants (HR: 1.49, 95% CI: 1.06–2.09) were more likely to have new onset depressive symptoms than no-sarcopenia peers.Conclusions: Both possible sarcopenia and sarcopenia, assessed using the AWGS 2019 criteria, were independent predictors for the occurrence of depressive symptoms among Chinese older adults. Our findings provided new evidence supporting the longitudinal connection between sarcopenia and mental health problems, it also provides further justification for timely identification and management of both possible sarcopenia and sarcopenia as part of comprehensive strategies to fight against depressive symptoms.
format	article
author	Ke Gao Wen-Zhuo Ma Wen-Zhuo Ma Scarlett Huck Bo-Lin Li Li Zhang Jiao Zhu Tian Li Dan Zhou
author_facet	Ke Gao Wen-Zhuo Ma Wen-Zhuo Ma Scarlett Huck Bo-Lin Li Li Zhang Jiao Zhu Tian Li Dan Zhou
author_sort	Ke Gao
title	Association Between Sarcopenia and Depressive Symptoms in Chinese Older Adults: Evidence From the China Health and Retirement Longitudinal Study
title_short	Association Between Sarcopenia and Depressive Symptoms in Chinese Older Adults: Evidence From the China Health and Retirement Longitudinal Study
title_full	Association Between Sarcopenia and Depressive Symptoms in Chinese Older Adults: Evidence From the China Health and Retirement Longitudinal Study
title_fullStr	Association Between Sarcopenia and Depressive Symptoms in Chinese Older Adults: Evidence From the China Health and Retirement Longitudinal Study
title_full_unstemmed	Association Between Sarcopenia and Depressive Symptoms in Chinese Older Adults: Evidence From the China Health and Retirement Longitudinal Study
title_sort	association between sarcopenia and depressive symptoms in chinese older adults: evidence from the china health and retirement longitudinal study
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/7c12b435113c4db3bd6523b0c9311105
work_keys_str_mv	AT kegao associationbetweensarcopeniaanddepressivesymptomsinchineseolderadultsevidencefromthechinahealthandretirementlongitudinalstudy AT wenzhuoma associationbetweensarcopeniaanddepressivesymptomsinchineseolderadultsevidencefromthechinahealthandretirementlongitudinalstudy AT wenzhuoma associationbetweensarcopeniaanddepressivesymptomsinchineseolderadultsevidencefromthechinahealthandretirementlongitudinalstudy AT scarletthuck associationbetweensarcopeniaanddepressivesymptomsinchineseolderadultsevidencefromthechinahealthandretirementlongitudinalstudy AT bolinli associationbetweensarcopeniaanddepressivesymptomsinchineseolderadultsevidencefromthechinahealthandretirementlongitudinalstudy AT lizhang associationbetweensarcopeniaanddepressivesymptomsinchineseolderadultsevidencefromthechinahealthandretirementlongitudinalstudy AT jiaozhu associationbetweensarcopeniaanddepressivesymptomsinchineseolderadultsevidencefromthechinahealthandretirementlongitudinalstudy AT tianli associationbetweensarcopeniaanddepressivesymptomsinchineseolderadultsevidencefromthechinahealthandretirementlongitudinalstudy AT danzhou associationbetweensarcopeniaanddepressivesymptomsinchineseolderadultsevidencefromthechinahealthandretirementlongitudinalstudy
_version_	1718425935161589760

Association Between Sarcopenia and Depressive Symptoms in Chinese Older Adults: Evidence From the China Health and Retirement Longitudinal Study

Ejemplares similares