Coexistence of Prefibrotic Myelofibrosis with Monoclonal Gammopathy of Undetermined Significance: A Case Report

The coexistence of dual hematological neoplasms is an unusual and challenging presentation due to the different combination of etiopathology. The presentation of synchronous dual hematological malignancies can be one of the 3 types: myeloid + lymphoid or dual lymphoid or dual myeloid. Here, we are r...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Omar M. Ismail, Aliaa Amer, Feryal A. Ibrahim, Mohammad Abu-Tineh, Mohamed A. Yassin
Formato:	article
Lenguaje:	EN
Publicado:	Karger Publishers 2021
Materias:	myeloproliferative neoplasm prefibrotic phase of primary myelofibrosis monoclonal gammopathy of undetermined significance coexistence second malignancies Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/7c1ee90c32314028ba3c064f278f563e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:7c1ee90c32314028ba3c064f278f563e
record_format	dspace
spelling	oai:doaj.org-article:7c1ee90c32314028ba3c064f278f563e2021-11-11T10:40:45ZCoexistence of Prefibrotic Myelofibrosis with Monoclonal Gammopathy of Undetermined Significance: A Case Report1662-657510.1159/000516746https://doaj.org/article/7c1ee90c32314028ba3c064f278f563e2021-10-01T00:00:00Zhttps://www.karger.com/Article/FullText/516746https://doaj.org/toc/1662-6575The coexistence of dual hematological neoplasms is an unusual and challenging presentation due to the different combination of etiopathology. The presentation of synchronous dual hematological malignancies can be one of the 3 types: myeloid + lymphoid or dual lymphoid or dual myeloid. Here, we are reporting a case of a 53-year-old male with simultaneous presence of JAK2 V617F-positive myeloproliferative neoplasm with features favoring prefibrotic phase of primary myelofibrosis (pre-PMF) in combination with monoclonal gammopathy of undetermined significance (MGUS). In such cases of simultaneous existence of dual hematological neoplasm management, it is recommended to treat the more aggressive one. Currently, our management plan is focusing on treating the pre-PMF and observation of MGUS with regular monitoring for transformation to MM.Omar M. IsmailAliaa AmerFeryal A. IbrahimMohammad Abu-TinehMohamed A. YassinKarger Publishersarticlemyeloproliferative neoplasmprefibrotic phase of primary myelofibrosismonoclonal gammopathy of undetermined significancecoexistencesecond malignanciesNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCase Reports in Oncology, Vol 14, Iss 3, Pp 1435-1440 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	myeloproliferative neoplasm prefibrotic phase of primary myelofibrosis monoclonal gammopathy of undetermined significance coexistence second malignancies Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	myeloproliferative neoplasm prefibrotic phase of primary myelofibrosis monoclonal gammopathy of undetermined significance coexistence second malignancies Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Omar M. Ismail Aliaa Amer Feryal A. Ibrahim Mohammad Abu-Tineh Mohamed A. Yassin Coexistence of Prefibrotic Myelofibrosis with Monoclonal Gammopathy of Undetermined Significance: A Case Report
description	The coexistence of dual hematological neoplasms is an unusual and challenging presentation due to the different combination of etiopathology. The presentation of synchronous dual hematological malignancies can be one of the 3 types: myeloid + lymphoid or dual lymphoid or dual myeloid. Here, we are reporting a case of a 53-year-old male with simultaneous presence of JAK2 V617F-positive myeloproliferative neoplasm with features favoring prefibrotic phase of primary myelofibrosis (pre-PMF) in combination with monoclonal gammopathy of undetermined significance (MGUS). In such cases of simultaneous existence of dual hematological neoplasm management, it is recommended to treat the more aggressive one. Currently, our management plan is focusing on treating the pre-PMF and observation of MGUS with regular monitoring for transformation to MM.
format	article
author	Omar M. Ismail Aliaa Amer Feryal A. Ibrahim Mohammad Abu-Tineh Mohamed A. Yassin
author_facet	Omar M. Ismail Aliaa Amer Feryal A. Ibrahim Mohammad Abu-Tineh Mohamed A. Yassin
author_sort	Omar M. Ismail
title	Coexistence of Prefibrotic Myelofibrosis with Monoclonal Gammopathy of Undetermined Significance: A Case Report
title_short	Coexistence of Prefibrotic Myelofibrosis with Monoclonal Gammopathy of Undetermined Significance: A Case Report
title_full	Coexistence of Prefibrotic Myelofibrosis with Monoclonal Gammopathy of Undetermined Significance: A Case Report
title_fullStr	Coexistence of Prefibrotic Myelofibrosis with Monoclonal Gammopathy of Undetermined Significance: A Case Report
title_full_unstemmed	Coexistence of Prefibrotic Myelofibrosis with Monoclonal Gammopathy of Undetermined Significance: A Case Report
title_sort	coexistence of prefibrotic myelofibrosis with monoclonal gammopathy of undetermined significance: a case report
publisher	Karger Publishers
publishDate	2021
url	https://doaj.org/article/7c1ee90c32314028ba3c064f278f563e
work_keys_str_mv	AT omarmismail coexistenceofprefibroticmyelofibrosiswithmonoclonalgammopathyofundeterminedsignificanceacasereport AT aliaaamer coexistenceofprefibroticmyelofibrosiswithmonoclonalgammopathyofundeterminedsignificanceacasereport AT feryalaibrahim coexistenceofprefibroticmyelofibrosiswithmonoclonalgammopathyofundeterminedsignificanceacasereport AT mohammadabutineh coexistenceofprefibroticmyelofibrosiswithmonoclonalgammopathyofundeterminedsignificanceacasereport AT mohamedayassin coexistenceofprefibroticmyelofibrosiswithmonoclonalgammopathyofundeterminedsignificanceacasereport
_version_	1718439140064755712

Coexistence of Prefibrotic Myelofibrosis with Monoclonal Gammopathy of Undetermined Significance: A Case Report

Ejemplares similares