Locus coeruleus-CA1 projections are involved in chronic depressive stress-induced hippocampal vulnerability to transient global ischaemia

Depression and transient ischaemic attacks are tightly regulated but the neural circuits underlying depression-modulated ischaemic injury are not known. Here, the authors show that the locus coeruleus-CA1 pathway is involved in depression-associated ischaemia susceptibility.

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Autores principales:	Qian Zhang, Dian Xing Hu, Feng He, Chun Yang Li, Guang Jian Qi, Hong Wei Cai, Tong Xia Li, Jie Ming, Pei Zhang, Xiao Qian Chen, Bo Tian
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7c22149bfacf4ac3806ebd64dff93286
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spelling	oai:doaj.org-article:7c22149bfacf4ac3806ebd64dff932862021-12-02T15:35:58ZLocus coeruleus-CA1 projections are involved in chronic depressive stress-induced hippocampal vulnerability to transient global ischaemia10.1038/s41467-019-10795-92041-1723https://doaj.org/article/7c22149bfacf4ac3806ebd64dff932862019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10795-9https://doaj.org/toc/2041-1723Depression and transient ischaemic attacks are tightly regulated but the neural circuits underlying depression-modulated ischaemic injury are not known. Here, the authors show that the locus coeruleus-CA1 pathway is involved in depression-associated ischaemia susceptibility.Qian ZhangDian Xing HuFeng HeChun Yang LiGuang Jian QiHong Wei CaiTong Xia LiJie MingPei ZhangXiao Qian ChenBo TianNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qian Zhang Dian Xing Hu Feng He Chun Yang Li Guang Jian Qi Hong Wei Cai Tong Xia Li Jie Ming Pei Zhang Xiao Qian Chen Bo Tian Locus coeruleus-CA1 projections are involved in chronic depressive stress-induced hippocampal vulnerability to transient global ischaemia
description	Depression and transient ischaemic attacks are tightly regulated but the neural circuits underlying depression-modulated ischaemic injury are not known. Here, the authors show that the locus coeruleus-CA1 pathway is involved in depression-associated ischaemia susceptibility.
format	article
author	Qian Zhang Dian Xing Hu Feng He Chun Yang Li Guang Jian Qi Hong Wei Cai Tong Xia Li Jie Ming Pei Zhang Xiao Qian Chen Bo Tian
author_facet	Qian Zhang Dian Xing Hu Feng He Chun Yang Li Guang Jian Qi Hong Wei Cai Tong Xia Li Jie Ming Pei Zhang Xiao Qian Chen Bo Tian
author_sort	Qian Zhang
title	Locus coeruleus-CA1 projections are involved in chronic depressive stress-induced hippocampal vulnerability to transient global ischaemia
title_short	Locus coeruleus-CA1 projections are involved in chronic depressive stress-induced hippocampal vulnerability to transient global ischaemia
title_full	Locus coeruleus-CA1 projections are involved in chronic depressive stress-induced hippocampal vulnerability to transient global ischaemia
title_fullStr	Locus coeruleus-CA1 projections are involved in chronic depressive stress-induced hippocampal vulnerability to transient global ischaemia
title_full_unstemmed	Locus coeruleus-CA1 projections are involved in chronic depressive stress-induced hippocampal vulnerability to transient global ischaemia
title_sort	locus coeruleus-ca1 projections are involved in chronic depressive stress-induced hippocampal vulnerability to transient global ischaemia
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/7c22149bfacf4ac3806ebd64dff93286
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Locus coeruleus-CA1 projections are involved in chronic depressive stress-induced hippocampal vulnerability to transient global ischaemia

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