SYK-3BP2 Pathway Activity in Parenchymal and Myeloid Cells Is a Key Pathogenic Factor in Metabolic SteatohepatitisSummary

SYK-3BP2 Pathway Activity in Parenchymal and Myeloid Cells Is a Key Pathogenic Factor in Metabolic SteatohepatitisSummary

Background & Aims: Spleen tyrosine kinase (SYK) signaling pathway regulates critical processes in innate immunity, but its role in parenchymal cells remains elusive in chronic liver diseases. We investigate the relative contribution of SYK and its substrate c-Abl Src homology 3 domain-bindin...

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Autores principales: Carmelo Luci, Elodie Vieira, Manon Bourinet, Déborah Rousseau, Stéphanie Bonnafous, Stéphanie Patouraux, Lauren Lefevre, Frederic Larbret, Virginie Prod’homme, Antonio Iannelli, Albert Tran, Rodolphe Anty, Béatrice Bailly-Maitre, Marcel Deckert, Philippe Gual
Formato: article
Lenguaje:EN
Publicado: Elsevier 2022
Materias:
SYK
3BP2
TREM1
TLR4
MAFLD
NASH
Diseases of the digestive system. Gastroenterology
RC799-869
Acceso en línea:https://doaj.org/article/7c2834e876ae418c87a2d3e981267d10
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