Multiplexed live-cell profiling with Raman probes
Currently relatively few functional probes for Raman-based live-cell profiling exist. Here the authors build on their previous ultra-bright Raman dots to devise a 14-plexed Raman probe panel to quantify cell surface proteins, endocytosis activities and metabolic dynamics of single live cells.
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Nature Portfolio
2021
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oai:doaj.org-article:7c2db342937a4bf5bc045156cf135ef12021-12-02T17:34:47ZMultiplexed live-cell profiling with Raman probes10.1038/s41467-021-23700-02041-1723https://doaj.org/article/7c2db342937a4bf5bc045156cf135ef12021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23700-0https://doaj.org/toc/2041-1723Currently relatively few functional probes for Raman-based live-cell profiling exist. Here the authors build on their previous ultra-bright Raman dots to devise a 14-plexed Raman probe panel to quantify cell surface proteins, endocytosis activities and metabolic dynamics of single live cells.Chen ChenZhilun ZhaoNaixin QianShixuan WeiFanghao HuWei MinNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
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Science Q Chen Chen Zhilun Zhao Naixin Qian Shixuan Wei Fanghao Hu Wei Min Multiplexed live-cell profiling with Raman probes |
description |
Currently relatively few functional probes for Raman-based live-cell profiling exist. Here the authors build on their previous ultra-bright Raman dots to devise a 14-plexed Raman probe panel to quantify cell surface proteins, endocytosis activities and metabolic dynamics of single live cells. |
format |
article |
author |
Chen Chen Zhilun Zhao Naixin Qian Shixuan Wei Fanghao Hu Wei Min |
author_facet |
Chen Chen Zhilun Zhao Naixin Qian Shixuan Wei Fanghao Hu Wei Min |
author_sort |
Chen Chen |
title |
Multiplexed live-cell profiling with Raman probes |
title_short |
Multiplexed live-cell profiling with Raman probes |
title_full |
Multiplexed live-cell profiling with Raman probes |
title_fullStr |
Multiplexed live-cell profiling with Raman probes |
title_full_unstemmed |
Multiplexed live-cell profiling with Raman probes |
title_sort |
multiplexed live-cell profiling with raman probes |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/7c2db342937a4bf5bc045156cf135ef1 |
work_keys_str_mv |
AT chenchen multiplexedlivecellprofilingwithramanprobes AT zhilunzhao multiplexedlivecellprofilingwithramanprobes AT naixinqian multiplexedlivecellprofilingwithramanprobes AT shixuanwei multiplexedlivecellprofilingwithramanprobes AT fanghaohu multiplexedlivecellprofilingwithramanprobes AT weimin multiplexedlivecellprofilingwithramanprobes |
_version_ |
1718379949277052928 |