Calcifying nanoparticles associated encrusted urinary bladder cystitis

Tomislav M Jelic1, Rod Roque1, Uzay Yasar2, Shayna B Tomchin1, Jose M Serrato2, Samuel G Deem3, James P Tierney3, Ho-Huang Chang11Department of Pathology Charleston Area Medical Center, Charleston WV, USA; 2Urology Center of Charleston, Charleston WV, USA; 3Urologic-Surgical Assoc. of Charleston, Ch...

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Autores principales:	Tomislav M Jelic, Rod Roque, Uzay Yasar, Shayna B Tomchin, Jose M Serrato, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2008
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/7c3d8d0bb42d44cda5337b9ace447dc8
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spelling	oai:doaj.org-article:7c3d8d0bb42d44cda5337b9ace447dc82021-12-02T02:44:04ZCalcifying nanoparticles associated encrusted urinary bladder cystitis1176-91141178-2013https://doaj.org/article/7c3d8d0bb42d44cda5337b9ace447dc82008-10-01T00:00:00Zhttp://www.dovepress.com/calcifying-nanoparticles-associated-encrusted-urinary-bladder-cystitis-a2438https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Tomislav M Jelic1, Rod Roque1, Uzay Yasar2, Shayna B Tomchin1, Jose M Serrato2, Samuel G Deem3, James P Tierney3, Ho-Huang Chang11Department of Pathology Charleston Area Medical Center, Charleston WV, USA; 2Urology Center of Charleston, Charleston WV, USA; 3Urologic-Surgical Assoc. of Charleston, Charleston WV, USAAbstract: Encrusted cystitis is a subtype of chronic cystitis characterized by multiple calcifications in the form of&nbsp;plaques located in the interstitium of the urinary bladder mucosa and frequently associated with mucosal ulcers. It is a very rare disease of controversial etiology. Our transmission electron microscopy of the calcified plaques of encrusted cystitis has revealed that the smallest formed particles (elementary units) of these calcifications are electron-dense shells surrounding an electron lucent core, diagnostic of calcifying nanoparticles (previously called nanobacteria). We pioneer the notion that calcifying nanoparticles are the causative agents of encrusted urinary bladder cystitis.Keywords: calcifying nanoparticles, nanobacteria, encrusted cystitis Tomislav M JelicRod RoqueUzay YasarShayna B TomchinJose M Serratoet alDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2008, Iss Issue 3, Pp 385-390 (2008)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Tomislav M Jelic Rod Roque Uzay Yasar Shayna B Tomchin Jose M Serrato et al Calcifying nanoparticles associated encrusted urinary bladder cystitis
description	Tomislav M Jelic1, Rod Roque1, Uzay Yasar2, Shayna B Tomchin1, Jose M Serrato2, Samuel G Deem3, James P Tierney3, Ho-Huang Chang11Department of Pathology Charleston Area Medical Center, Charleston WV, USA; 2Urology Center of Charleston, Charleston WV, USA; 3Urologic-Surgical Assoc. of Charleston, Charleston WV, USAAbstract: Encrusted cystitis is a subtype of chronic cystitis characterized by multiple calcifications in the form of&nbsp;plaques located in the interstitium of the urinary bladder mucosa and frequently associated with mucosal ulcers. It is a very rare disease of controversial etiology. Our transmission electron microscopy of the calcified plaques of encrusted cystitis has revealed that the smallest formed particles (elementary units) of these calcifications are electron-dense shells surrounding an electron lucent core, diagnostic of calcifying nanoparticles (previously called nanobacteria). We pioneer the notion that calcifying nanoparticles are the causative agents of encrusted urinary bladder cystitis.Keywords: calcifying nanoparticles, nanobacteria, encrusted cystitis
format	article
author	Tomislav M Jelic Rod Roque Uzay Yasar Shayna B Tomchin Jose M Serrato et al
author_facet	Tomislav M Jelic Rod Roque Uzay Yasar Shayna B Tomchin Jose M Serrato et al
author_sort	Tomislav M Jelic
title	Calcifying nanoparticles associated encrusted urinary bladder cystitis
title_short	Calcifying nanoparticles associated encrusted urinary bladder cystitis
title_full	Calcifying nanoparticles associated encrusted urinary bladder cystitis
title_fullStr	Calcifying nanoparticles associated encrusted urinary bladder cystitis
title_full_unstemmed	Calcifying nanoparticles associated encrusted urinary bladder cystitis
title_sort	calcifying nanoparticles associated encrusted urinary bladder cystitis
publisher	Dove Medical Press
publishDate	2008
url	https://doaj.org/article/7c3d8d0bb42d44cda5337b9ace447dc8
work_keys_str_mv	AT tomislavmjelic calcifyingnanoparticlesassociatedencrustedurinarybladdercystitis AT rodroque calcifyingnanoparticlesassociatedencrustedurinarybladdercystitis AT uzayyasar calcifyingnanoparticlesassociatedencrustedurinarybladdercystitis AT shaynabtomchin calcifyingnanoparticlesassociatedencrustedurinarybladdercystitis AT josemserrato calcifyingnanoparticlesassociatedencrustedurinarybladdercystitis AT etal calcifyingnanoparticlesassociatedencrustedurinarybladdercystitis
_version_	1718402172619587584

Calcifying nanoparticles associated encrusted urinary bladder cystitis

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