A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging
D-luciferin is the standard bioluminescent substrate for in vitro and in vivo imaging. Here the authors introduce AkaLumine-HCl, a soluble luciferin analogue with a near-infrared emission maximum, which allows deep tissue imaging at lower concentrations than D-luciferin.
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Nature Portfolio
2016
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oai:doaj.org-article:7c43d0c3cba6406684f84f686df358a92021-12-02T16:49:59ZA luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging10.1038/ncomms118562041-1723https://doaj.org/article/7c43d0c3cba6406684f84f686df358a92016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11856https://doaj.org/toc/2041-1723D-luciferin is the standard bioluminescent substrate for in vitro and in vivo imaging. Here the authors introduce AkaLumine-HCl, a soluble luciferin analogue with a near-infrared emission maximum, which allows deep tissue imaging at lower concentrations than D-luciferin.Takahiro KuchimaruSatoshi IwanoMasahiro KiyamaShun MitsumataTetsuya KadonosonoHaruki NiwaShojiro MakiShinae Kizaka-KondohNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016) |
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Science Q Takahiro Kuchimaru Satoshi Iwano Masahiro Kiyama Shun Mitsumata Tetsuya Kadonosono Haruki Niwa Shojiro Maki Shinae Kizaka-Kondoh A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging |
description |
D-luciferin is the standard bioluminescent substrate for in vitro and in vivo imaging. Here the authors introduce AkaLumine-HCl, a soluble luciferin analogue with a near-infrared emission maximum, which allows deep tissue imaging at lower concentrations than D-luciferin. |
format |
article |
author |
Takahiro Kuchimaru Satoshi Iwano Masahiro Kiyama Shun Mitsumata Tetsuya Kadonosono Haruki Niwa Shojiro Maki Shinae Kizaka-Kondoh |
author_facet |
Takahiro Kuchimaru Satoshi Iwano Masahiro Kiyama Shun Mitsumata Tetsuya Kadonosono Haruki Niwa Shojiro Maki Shinae Kizaka-Kondoh |
author_sort |
Takahiro Kuchimaru |
title |
A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging |
title_short |
A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging |
title_full |
A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging |
title_fullStr |
A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging |
title_full_unstemmed |
A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging |
title_sort |
luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/7c43d0c3cba6406684f84f686df358a9 |
work_keys_str_mv |
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