Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam
Objectives: Men who have sex with men (MSM) are at risk of human papillomavirus (HPV)-related cancers, while published data are scarce. This study determined HPV prevalence and risk factors in MSM in Vietnam to inform HPV prevention strategies in this key population. Methods: A cross-sectional study...
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2021
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oai:doaj.org-article:7c472cfe37d045a2b7ec4bcd81da615c2021-11-30T04:14:08ZAnal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam1201-971210.1016/j.ijid.2021.09.016https://doaj.org/article/7c472cfe37d045a2b7ec4bcd81da615c2021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1201971221007189https://doaj.org/toc/1201-9712Objectives: Men who have sex with men (MSM) are at risk of human papillomavirus (HPV)-related cancers, while published data are scarce. This study determined HPV prevalence and risk factors in MSM in Vietnam to inform HPV prevention strategies in this key population. Methods: A cross-sectional study of 799 MSM aged 16-50 years was conducted in Vietnam in 2017-2018. Information was collected on risk behaviours, and knowledge of HPV and anal cancer; rectal swabs were taken to detect anal HPV infection. An in-house polymerase chain reaction and Genoflow HPV array test kit were used for HPV detection and genotyping. Results: The median age of the study participants was 25 years (range 18-52). Overall prevalence of any HPV and HPV16/18 infection was 32.3% and 11.0%, respectively. A higher prevalence of high-risk HPV infection to all 14 types tested was found in Ho Chi Minh City (30.9%) than in Hanoi (18.4%). High-risk HPV infection was associated with inconsistent condom use and history of engaging in sex under the influence of drugs (adjusted odds ratio (aOR), 2.27; 95% CI, 1.48-10.67), as well as having multiple sexual partners (aOR, 1.01; 95% CI, 1.00–1.02). Conclusions: High-risk anal HPV infections in Vietnamese MSM were significantly associated with risky sexual behaviours. A targeted HPV vaccination strategy would have substantial benefit for MSM in Vietnam.Le Anh Tuan, MD, PhDKiesha Prem, PhDQuang Duy Pham, MD, PhDZheng Quan Toh, PhDHau Phuc Tran, MD, PhDPhuc Duy Nguyen, MScChu Thi Ngoc Mai, BScLe Thi Khanh Ly, BScVan Cao, PhDTam-Duong Le-Ha, PhDNguyen Anh Tuan, PhDMark Jit, PhDKathryn Bright, BNMarc Brisson, PhDThuong Vu Nguyen, MD, PhDSuzanne Garland, MD, PhDDang Duc Anh, PhDNguyen Van Trang, PhDKim Mulholland, MD, PhDElsevierarticleMen who have sex with menMSMHPVRisk factorsVietnamInfectious and parasitic diseasesRC109-216ENInternational Journal of Infectious Diseases, Vol 112, Iss , Pp 136-143 (2021) |
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DOAJ |
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DOAJ |
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EN |
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Men who have sex with men MSM HPV Risk factors Vietnam Infectious and parasitic diseases RC109-216 |
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Men who have sex with men MSM HPV Risk factors Vietnam Infectious and parasitic diseases RC109-216 Le Anh Tuan, MD, PhD Kiesha Prem, PhD Quang Duy Pham, MD, PhD Zheng Quan Toh, PhD Hau Phuc Tran, MD, PhD Phuc Duy Nguyen, MSc Chu Thi Ngoc Mai, BSc Le Thi Khanh Ly, BSc Van Cao, PhD Tam-Duong Le-Ha, PhD Nguyen Anh Tuan, PhD Mark Jit, PhD Kathryn Bright, BN Marc Brisson, PhD Thuong Vu Nguyen, MD, PhD Suzanne Garland, MD, PhD Dang Duc Anh, PhD Nguyen Van Trang, PhD Kim Mulholland, MD, PhD Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam |
| description |
Objectives: Men who have sex with men (MSM) are at risk of human papillomavirus (HPV)-related cancers, while published data are scarce. This study determined HPV prevalence and risk factors in MSM in Vietnam to inform HPV prevention strategies in this key population. Methods: A cross-sectional study of 799 MSM aged 16-50 years was conducted in Vietnam in 2017-2018. Information was collected on risk behaviours, and knowledge of HPV and anal cancer; rectal swabs were taken to detect anal HPV infection. An in-house polymerase chain reaction and Genoflow HPV array test kit were used for HPV detection and genotyping. Results: The median age of the study participants was 25 years (range 18-52). Overall prevalence of any HPV and HPV16/18 infection was 32.3% and 11.0%, respectively. A higher prevalence of high-risk HPV infection to all 14 types tested was found in Ho Chi Minh City (30.9%) than in Hanoi (18.4%). High-risk HPV infection was associated with inconsistent condom use and history of engaging in sex under the influence of drugs (adjusted odds ratio (aOR), 2.27; 95% CI, 1.48-10.67), as well as having multiple sexual partners (aOR, 1.01; 95% CI, 1.00–1.02). Conclusions: High-risk anal HPV infections in Vietnamese MSM were significantly associated with risky sexual behaviours. A targeted HPV vaccination strategy would have substantial benefit for MSM in Vietnam. |
| format |
article |
| author |
Le Anh Tuan, MD, PhD Kiesha Prem, PhD Quang Duy Pham, MD, PhD Zheng Quan Toh, PhD Hau Phuc Tran, MD, PhD Phuc Duy Nguyen, MSc Chu Thi Ngoc Mai, BSc Le Thi Khanh Ly, BSc Van Cao, PhD Tam-Duong Le-Ha, PhD Nguyen Anh Tuan, PhD Mark Jit, PhD Kathryn Bright, BN Marc Brisson, PhD Thuong Vu Nguyen, MD, PhD Suzanne Garland, MD, PhD Dang Duc Anh, PhD Nguyen Van Trang, PhD Kim Mulholland, MD, PhD |
| author_facet |
Le Anh Tuan, MD, PhD Kiesha Prem, PhD Quang Duy Pham, MD, PhD Zheng Quan Toh, PhD Hau Phuc Tran, MD, PhD Phuc Duy Nguyen, MSc Chu Thi Ngoc Mai, BSc Le Thi Khanh Ly, BSc Van Cao, PhD Tam-Duong Le-Ha, PhD Nguyen Anh Tuan, PhD Mark Jit, PhD Kathryn Bright, BN Marc Brisson, PhD Thuong Vu Nguyen, MD, PhD Suzanne Garland, MD, PhD Dang Duc Anh, PhD Nguyen Van Trang, PhD Kim Mulholland, MD, PhD |
| author_sort |
Le Anh Tuan, MD, PhD |
| title |
Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam |
| title_short |
Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam |
| title_full |
Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam |
| title_fullStr |
Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam |
| title_full_unstemmed |
Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam |
| title_sort |
anal human papillomavirus prevalence and risk factors among men who have sex with men in vietnam |
| publisher |
Elsevier |
| publishDate |
2021 |
| url |
https://doaj.org/article/7c472cfe37d045a2b7ec4bcd81da615c |
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