Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall

Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall

The gaseous signalling molecule nitric oxide regulates vascular tone. Here, the authors show that nitric oxide is degraded by the enzyme cytoglobin in the vascular wall, and that mice lacking cytoglobin have reduced blood pressure and are less sensitive to angiotensin-mediated hypertension.

Guardado en:
Detalles Bibliográficos
Autores principales: Xiaoping Liu, Mohamed A. El-Mahdy, James Boslett, Saradhadevi Varadharaj, Craig Hemann, Tamer M. Abdelghany, Raed S. Ismail, Sean C. Little, Danlei Zhou, Le Thi Thanh Thuy, Norifumi Kawada, Jay L. Zweier
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/7c48b88ebe1f45628a4d604983c1bc11
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/7c48b88ebe1f45628a4d604983c1bc11

Ejemplares similares