Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination

Meiotic crossovers (COs) generate genetic variation and ensure proper chromosome segregation. Here, the authors develop a method for identifying COs at kilobase resolution in pooled recombinants using linked-read sequencing data, and apply it to investigate genome-wide CO landscapes of Arabidopsis t...

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Autores principales:	Hequan Sun, Beth A. Rowan, Pádraic J. Flood, Ronny Brandt, Janina Fuss, Angela M. Hancock, Richard W. Michelmore, Bruno Huettel, Korbinian Schneeberger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7c4b7b1beeff41c38b550e64c5ba8fad
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spelling	oai:doaj.org-article:7c4b7b1beeff41c38b550e64c5ba8fad2021-12-02T17:01:39ZLinked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination10.1038/s41467-019-12209-22041-1723https://doaj.org/article/7c4b7b1beeff41c38b550e64c5ba8fad2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12209-2https://doaj.org/toc/2041-1723Meiotic crossovers (COs) generate genetic variation and ensure proper chromosome segregation. Here, the authors develop a method for identifying COs at kilobase resolution in pooled recombinants using linked-read sequencing data, and apply it to investigate genome-wide CO landscapes of Arabidopsis thaliana.Hequan SunBeth A. RowanPádraic J. FloodRonny BrandtJanina FussAngela M. HancockRichard W. MichelmoreBruno HuettelKorbinian SchneebergerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hequan Sun Beth A. Rowan Pádraic J. Flood Ronny Brandt Janina Fuss Angela M. Hancock Richard W. Michelmore Bruno Huettel Korbinian Schneeberger Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination
description	Meiotic crossovers (COs) generate genetic variation and ensure proper chromosome segregation. Here, the authors develop a method for identifying COs at kilobase resolution in pooled recombinants using linked-read sequencing data, and apply it to investigate genome-wide CO landscapes of Arabidopsis thaliana.
format	article
author	Hequan Sun Beth A. Rowan Pádraic J. Flood Ronny Brandt Janina Fuss Angela M. Hancock Richard W. Michelmore Bruno Huettel Korbinian Schneeberger
author_facet	Hequan Sun Beth A. Rowan Pádraic J. Flood Ronny Brandt Janina Fuss Angela M. Hancock Richard W. Michelmore Bruno Huettel Korbinian Schneeberger
author_sort	Hequan Sun
title	Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination
title_short	Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination
title_full	Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination
title_fullStr	Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination
title_full_unstemmed	Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination
title_sort	linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/7c4b7b1beeff41c38b550e64c5ba8fad
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Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination

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