The H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN

Telomerase RNA (hTR) is transcribed as a 3′-extended precursor. Here the authors examine the processing of hTR precursors of various lengths and show that processing occurs in distinct steps involving different nucleases PARN and RRP6.

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Autores principales:	Chi-Kang Tseng, Hui-Fang Wang, Morgan R. Schroeder, Peter Baumann
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7c53ca334961462392633af0c6271d1f
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spelling	oai:doaj.org-article:7c53ca334961462392633af0c6271d1f2021-12-02T16:49:50ZThe H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN10.1038/s41467-018-07822-62041-1723https://doaj.org/article/7c53ca334961462392633af0c6271d1f2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07822-6https://doaj.org/toc/2041-1723Telomerase RNA (hTR) is transcribed as a 3′-extended precursor. Here the authors examine the processing of hTR precursors of various lengths and show that processing occurs in distinct steps involving different nucleases PARN and RRP6.Chi-Kang TsengHui-Fang WangMorgan R. SchroederPeter BaumannNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chi-Kang Tseng Hui-Fang Wang Morgan R. Schroeder Peter Baumann The H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN
description	Telomerase RNA (hTR) is transcribed as a 3′-extended precursor. Here the authors examine the processing of hTR precursors of various lengths and show that processing occurs in distinct steps involving different nucleases PARN and RRP6.
format	article
author	Chi-Kang Tseng Hui-Fang Wang Morgan R. Schroeder Peter Baumann
author_facet	Chi-Kang Tseng Hui-Fang Wang Morgan R. Schroeder Peter Baumann
author_sort	Chi-Kang Tseng
title	The H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN
title_short	The H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN
title_full	The H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN
title_fullStr	The H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN
title_full_unstemmed	The H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN
title_sort	h/aca complex disrupts triplex in htr precursor to permit processing by rrp6 and parn
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/7c53ca334961462392633af0c6271d1f
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The H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN

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