The H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN
Telomerase RNA (hTR) is transcribed as a 3′-extended precursor. Here the authors examine the processing of hTR precursors of various lengths and show that processing occurs in distinct steps involving different nucleases PARN and RRP6.
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Autores principales: | Chi-Kang Tseng, Hui-Fang Wang, Morgan R. Schroeder, Peter Baumann |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/7c53ca334961462392633af0c6271d1f |
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