Structural basis for the second step of group II intron splicing
Group II introns are large, self-splicing RNAs that catalyze their own excision from pre-mRNA molecules. Here the authors determine the 3.7 Å crystal structure of the group II intron in the stage immediately before the second step of splicing and present a complete model for the second step of group...
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Nature Portfolio
2018
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oai:doaj.org-article:7c5644150b6e47eb8f1cee53b217aef72021-12-02T14:39:44ZStructural basis for the second step of group II intron splicing10.1038/s41467-018-06678-02041-1723https://doaj.org/article/7c5644150b6e47eb8f1cee53b217aef72018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06678-0https://doaj.org/toc/2041-1723Group II introns are large, self-splicing RNAs that catalyze their own excision from pre-mRNA molecules. Here the authors determine the 3.7 Å crystal structure of the group II intron in the stage immediately before the second step of splicing and present a complete model for the second step of group II intron splicing.Russell T. ChanJessica K. PetersAaron R. RobartTimothy WiryamanKanagalaghatta R. RajashankarNavtej ToorNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018) |
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Science Q Russell T. Chan Jessica K. Peters Aaron R. Robart Timothy Wiryaman Kanagalaghatta R. Rajashankar Navtej Toor Structural basis for the second step of group II intron splicing |
description |
Group II introns are large, self-splicing RNAs that catalyze their own excision from pre-mRNA molecules. Here the authors determine the 3.7 Å crystal structure of the group II intron in the stage immediately before the second step of splicing and present a complete model for the second step of group II intron splicing. |
format |
article |
author |
Russell T. Chan Jessica K. Peters Aaron R. Robart Timothy Wiryaman Kanagalaghatta R. Rajashankar Navtej Toor |
author_facet |
Russell T. Chan Jessica K. Peters Aaron R. Robart Timothy Wiryaman Kanagalaghatta R. Rajashankar Navtej Toor |
author_sort |
Russell T. Chan |
title |
Structural basis for the second step of group II intron splicing |
title_short |
Structural basis for the second step of group II intron splicing |
title_full |
Structural basis for the second step of group II intron splicing |
title_fullStr |
Structural basis for the second step of group II intron splicing |
title_full_unstemmed |
Structural basis for the second step of group II intron splicing |
title_sort |
structural basis for the second step of group ii intron splicing |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/7c5644150b6e47eb8f1cee53b217aef7 |
work_keys_str_mv |
AT russelltchan structuralbasisforthesecondstepofgroupiiintronsplicing AT jessicakpeters structuralbasisforthesecondstepofgroupiiintronsplicing AT aaronrrobart structuralbasisforthesecondstepofgroupiiintronsplicing AT timothywiryaman structuralbasisforthesecondstepofgroupiiintronsplicing AT kanagalaghattarrajashankar structuralbasisforthesecondstepofgroupiiintronsplicing AT navtejtoor structuralbasisforthesecondstepofgroupiiintronsplicing |
_version_ |
1718390541191741440 |