Structural basis for the second step of group II intron splicing

Group II introns are large, self-splicing RNAs that catalyze their own excision from pre-mRNA molecules. Here the authors determine the 3.7 Å crystal structure of the group II intron in the stage immediately before the second step of splicing and present a complete model for the second step of group...

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Autores principales: Russell T. Chan, Jessica K. Peters, Aaron R. Robart, Timothy Wiryaman, Kanagalaghatta R. Rajashankar, Navtej Toor
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/7c5644150b6e47eb8f1cee53b217aef7
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spelling oai:doaj.org-article:7c5644150b6e47eb8f1cee53b217aef72021-12-02T14:39:44ZStructural basis for the second step of group II intron splicing10.1038/s41467-018-06678-02041-1723https://doaj.org/article/7c5644150b6e47eb8f1cee53b217aef72018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06678-0https://doaj.org/toc/2041-1723Group II introns are large, self-splicing RNAs that catalyze their own excision from pre-mRNA molecules. Here the authors determine the 3.7 Å crystal structure of the group II intron in the stage immediately before the second step of splicing and present a complete model for the second step of group II intron splicing.Russell T. ChanJessica K. PetersAaron R. RobartTimothy WiryamanKanagalaghatta R. RajashankarNavtej ToorNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Russell T. Chan
Jessica K. Peters
Aaron R. Robart
Timothy Wiryaman
Kanagalaghatta R. Rajashankar
Navtej Toor
Structural basis for the second step of group II intron splicing
description Group II introns are large, self-splicing RNAs that catalyze their own excision from pre-mRNA molecules. Here the authors determine the 3.7 Å crystal structure of the group II intron in the stage immediately before the second step of splicing and present a complete model for the second step of group II intron splicing.
format article
author Russell T. Chan
Jessica K. Peters
Aaron R. Robart
Timothy Wiryaman
Kanagalaghatta R. Rajashankar
Navtej Toor
author_facet Russell T. Chan
Jessica K. Peters
Aaron R. Robart
Timothy Wiryaman
Kanagalaghatta R. Rajashankar
Navtej Toor
author_sort Russell T. Chan
title Structural basis for the second step of group II intron splicing
title_short Structural basis for the second step of group II intron splicing
title_full Structural basis for the second step of group II intron splicing
title_fullStr Structural basis for the second step of group II intron splicing
title_full_unstemmed Structural basis for the second step of group II intron splicing
title_sort structural basis for the second step of group ii intron splicing
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/7c5644150b6e47eb8f1cee53b217aef7
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