Length of stay following percutaneous left atrial appendage occlusion: Data from the prospective, multicenter Amplatzer Amulet Occluder Observational Study.

<h4>Aims</h4>To evaluate factors influencing the length of stay in patients undergoing percutaneous left atrial appendage occlusion (LAAO).<h4>Methods and results</h4>Patient characteristics, procedural data and the occurrence of serious adverse events were analyzed from the...

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Autores principales:	Kerstin Piayda, Shazia Afzal, Jens Erik Nielsen-Kudsk, Boris Schmidt, Patrizio Mazzone, Sergio Berti, Sven Fischer, Juha Lund, Matteo Montorfano, David Hildick-Smith, Ryan Gage, Hong Zhao, Tobias Zeus
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7c5db05e84af475baf5cf93fa641e01c
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spelling	oai:doaj.org-article:7c5db05e84af475baf5cf93fa641e01c2021-12-02T20:19:38ZLength of stay following percutaneous left atrial appendage occlusion: Data from the prospective, multicenter Amplatzer Amulet Occluder Observational Study.1932-620310.1371/journal.pone.0255721https://doaj.org/article/7c5db05e84af475baf5cf93fa641e01c2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0255721https://doaj.org/toc/1932-6203<h4>Aims</h4>To evaluate factors influencing the length of stay in patients undergoing percutaneous left atrial appendage occlusion (LAAO).<h4>Methods and results</h4>Patient characteristics, procedural data and the occurrence of serious adverse events were analyzed from the AmplatzerTM AmuletTM Occluder Observational Study. Patients were divided into three groups: same day (S, 0day, n = 60, 5.6%) early (E, 1day, n = 526, 48.9%), regular (R, 2-3days, n = 338, 31.4%) and late (L, ≥4days, n = 152, 14.1%) discharge and followed up for 60 days. Procedure and device related SAE during the in-hospital stay (S: 0.0% vs. E: 1.0% vs. R: 2.1% vs. L: 23%, p<0.0001) were a major trigger for a prolonged in-hospital stay. Of the 37 subjects in the late discharge group with an SAE prior to discharge, cardiac or bleeding complications were the most common underlying conditions, occurring in 26 subjects. Multinomial logistic analysis only identified HAS-BLED score as an independent influencing factor (p = 0.04) for a late discharge. After 60 days, mortality tended to be greatest in the late discharge group (S: 0.0% vs. E: 1.0% vs. R: 1.2% vs. L: 3.3%, p = 0.1066).<h4>Conclusion</h4>Over half of the subjects receiving an Amplatzer Amulet occluder were discharged within 1 day of the implant procedure. Serious adverse events were a major trigger for a late discharge after LAAO. Increased HAS-BLED score was associated with a prolonged in-hospital stay.Kerstin PiaydaShazia AfzalJens Erik Nielsen-KudskBoris SchmidtPatrizio MazzoneSergio BertiSven FischerJuha LundMatteo MontorfanoDavid Hildick-SmithRyan GageHong ZhaoTobias ZeusPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0255721 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kerstin Piayda Shazia Afzal Jens Erik Nielsen-Kudsk Boris Schmidt Patrizio Mazzone Sergio Berti Sven Fischer Juha Lund Matteo Montorfano David Hildick-Smith Ryan Gage Hong Zhao Tobias Zeus Length of stay following percutaneous left atrial appendage occlusion: Data from the prospective, multicenter Amplatzer Amulet Occluder Observational Study.
description	<h4>Aims</h4>To evaluate factors influencing the length of stay in patients undergoing percutaneous left atrial appendage occlusion (LAAO).<h4>Methods and results</h4>Patient characteristics, procedural data and the occurrence of serious adverse events were analyzed from the AmplatzerTM AmuletTM Occluder Observational Study. Patients were divided into three groups: same day (S, 0day, n = 60, 5.6%) early (E, 1day, n = 526, 48.9%), regular (R, 2-3days, n = 338, 31.4%) and late (L, ≥4days, n = 152, 14.1%) discharge and followed up for 60 days. Procedure and device related SAE during the in-hospital stay (S: 0.0% vs. E: 1.0% vs. R: 2.1% vs. L: 23%, p<0.0001) were a major trigger for a prolonged in-hospital stay. Of the 37 subjects in the late discharge group with an SAE prior to discharge, cardiac or bleeding complications were the most common underlying conditions, occurring in 26 subjects. Multinomial logistic analysis only identified HAS-BLED score as an independent influencing factor (p = 0.04) for a late discharge. After 60 days, mortality tended to be greatest in the late discharge group (S: 0.0% vs. E: 1.0% vs. R: 1.2% vs. L: 3.3%, p = 0.1066).<h4>Conclusion</h4>Over half of the subjects receiving an Amplatzer Amulet occluder were discharged within 1 day of the implant procedure. Serious adverse events were a major trigger for a late discharge after LAAO. Increased HAS-BLED score was associated with a prolonged in-hospital stay.
format	article
author	Kerstin Piayda Shazia Afzal Jens Erik Nielsen-Kudsk Boris Schmidt Patrizio Mazzone Sergio Berti Sven Fischer Juha Lund Matteo Montorfano David Hildick-Smith Ryan Gage Hong Zhao Tobias Zeus
author_facet	Kerstin Piayda Shazia Afzal Jens Erik Nielsen-Kudsk Boris Schmidt Patrizio Mazzone Sergio Berti Sven Fischer Juha Lund Matteo Montorfano David Hildick-Smith Ryan Gage Hong Zhao Tobias Zeus
author_sort	Kerstin Piayda
title	Length of stay following percutaneous left atrial appendage occlusion: Data from the prospective, multicenter Amplatzer Amulet Occluder Observational Study.
title_short	Length of stay following percutaneous left atrial appendage occlusion: Data from the prospective, multicenter Amplatzer Amulet Occluder Observational Study.
title_full	Length of stay following percutaneous left atrial appendage occlusion: Data from the prospective, multicenter Amplatzer Amulet Occluder Observational Study.
title_fullStr	Length of stay following percutaneous left atrial appendage occlusion: Data from the prospective, multicenter Amplatzer Amulet Occluder Observational Study.
title_full_unstemmed	Length of stay following percutaneous left atrial appendage occlusion: Data from the prospective, multicenter Amplatzer Amulet Occluder Observational Study.
title_sort	length of stay following percutaneous left atrial appendage occlusion: data from the prospective, multicenter amplatzer amulet occluder observational study.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/7c5db05e84af475baf5cf93fa641e01c
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Length of stay following percutaneous left atrial appendage occlusion: Data from the prospective, multicenter Amplatzer Amulet Occluder Observational Study.

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