Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease
Aim. To assess the extent of the lower limb arterial calcification and to evaluate the long-term outcomes of percutaneous transluminal balloon angioplasty (PTBA) in patients with diabetes mellitus (DM), critical limb ischemia (CLI) and chronic kidney disease (CKD). Materials and Methods. 94 patien...
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Endocrinology Research Centre
2013
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oai:doaj.org-article:7c5f174736214dfba9492d130072356e2021-11-14T09:00:18ZClinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease2072-03512072-037810.14341/DM2013485-94https://doaj.org/article/7c5f174736214dfba9492d130072356e2013-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6259https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To assess the extent of the lower limb arterial calcification and to evaluate the long-term outcomes of percutaneous transluminal balloon angioplasty (PTBA) in patients with diabetes mellitus (DM), critical limb ischemia (CLI) and chronic kidney disease (CKD). Materials and Methods. 94 patients with CLI formed two groups (CKD-positive and CDK-negative). Quantitative assessment of tibial arterial calcification was performed with non-contrast CT. Outcomes of angioplasty were monitored during the 18?6 months of the follow-up period by means of duplex ultrasonography. Results. Long-term outcomes of PTBA were significantly worse in patients with CKD. Nevertheless, limb preservation and survival rates were relatively satisfactory in both groups (74% and 72%, respectively). Conclusion. PTBA in patients with DM, CLI and CKD presents a technical challenge. Despite that, in many cases the endovascular intervention allows avoiding high-level amputations and improves survival rates.Natalya Leonidovna AyubovaOlga Nikolaevna BondarenkoGagik Radikovich GalstyanOksana Vladimirovna ManchenkoIvan Ivanovich DedovEndocrinology Research Centrearticlediabetes mellituscritical limb ischemiapercutaneous transluminal balloon angioplastytibial artery calcificationduplex ultrasonographyNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 16, Iss 4, Pp 85-94 (2013) |
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diabetes mellitus critical limb ischemia percutaneous transluminal balloon angioplasty tibial artery calcification duplex ultrasonography Nutritional diseases. Deficiency diseases RC620-627 |
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diabetes mellitus critical limb ischemia percutaneous transluminal balloon angioplasty tibial artery calcification duplex ultrasonography Nutritional diseases. Deficiency diseases RC620-627 Natalya Leonidovna Ayubova Olga Nikolaevna Bondarenko Gagik Radikovich Galstyan Oksana Vladimirovna Manchenko Ivan Ivanovich Dedov Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease |
description |
Aim. To assess the extent of the lower limb arterial calcification and to evaluate the long-term outcomes of percutaneous transluminal balloon angioplasty (PTBA) in patients with diabetes mellitus (DM), critical limb ischemia (CLI) and chronic kidney disease (CKD). Materials and Methods. 94 patients with CLI formed two groups (CKD-positive and CDK-negative). Quantitative assessment of tibial arterial calcification was performed with non-contrast CT. Outcomes of angioplasty were monitored during the 18?6 months of the follow-up period by means of duplex ultrasonography. Results. Long-term outcomes of PTBA were significantly worse in patients with CKD. Nevertheless, limb preservation and survival rates were relatively satisfactory in both groups (74% and 72%, respectively). Conclusion. PTBA in patients with DM, CLI and CKD presents a technical challenge. Despite that, in many cases the endovascular intervention allows avoiding high-level amputations and improves survival rates. |
format |
article |
author |
Natalya Leonidovna Ayubova Olga Nikolaevna Bondarenko Gagik Radikovich Galstyan Oksana Vladimirovna Manchenko Ivan Ivanovich Dedov |
author_facet |
Natalya Leonidovna Ayubova Olga Nikolaevna Bondarenko Gagik Radikovich Galstyan Oksana Vladimirovna Manchenko Ivan Ivanovich Dedov |
author_sort |
Natalya Leonidovna Ayubova |
title |
Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease |
title_short |
Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease |
title_full |
Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease |
title_fullStr |
Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease |
title_full_unstemmed |
Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease |
title_sort |
clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease |
publisher |
Endocrinology Research Centre |
publishDate |
2013 |
url |
https://doaj.org/article/7c5f174736214dfba9492d130072356e |
work_keys_str_mv |
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1718429588898447360 |