Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease

Aim. To assess the extent of the lower limb arterial calcification and to evaluate the long-term outcomes of percutaneous transluminal balloon angioplasty (PTBA) in patients with diabetes mellitus (DM), critical limb ischemia (CLI) and chronic kidney disease (CKD). Materials and Methods. 94 patien...

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Autores principales: Natalya Leonidovna Ayubova, Olga Nikolaevna Bondarenko, Gagik Radikovich Galstyan, Oksana Vladimirovna Manchenko, Ivan Ivanovich Dedov
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RU
Publicado: Endocrinology Research Centre 2013
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Acceso en línea:https://doaj.org/article/7c5f174736214dfba9492d130072356e
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spelling oai:doaj.org-article:7c5f174736214dfba9492d130072356e2021-11-14T09:00:18ZClinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease2072-03512072-037810.14341/DM2013485-94https://doaj.org/article/7c5f174736214dfba9492d130072356e2013-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6259https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To assess the extent of the lower limb arterial calcification and to evaluate the long-term outcomes of percutaneous transluminal balloon angioplasty (PTBA) in patients with diabetes mellitus (DM), critical limb ischemia (CLI) and chronic kidney disease (CKD). Materials and Methods. 94 patients with CLI formed two groups (CKD-positive and CDK-negative). Quantitative assessment of tibial arterial calcification was performed with non-contrast CT. Outcomes of angioplasty were monitored during the 18?6 months of the follow-up period by means of duplex ultrasonography. Results.  Long-term outcomes of PTBA were significantly worse in patients with CKD. Nevertheless, limb preservation and survival rates were relatively satisfactory in both groups (74% and 72%, respectively). Conclusion. PTBA in patients with DM, CLI and CKD presents a technical challenge. Despite that, in many cases the endovascular intervention allows avoiding high-level amputations and improves survival rates.Natalya Leonidovna AyubovaOlga Nikolaevna BondarenkoGagik Radikovich GalstyanOksana Vladimirovna ManchenkoIvan Ivanovich DedovEndocrinology Research Centrearticlediabetes mellituscritical limb ischemiapercutaneous transluminal balloon angioplastytibial artery calcificationduplex ultrasonographyNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 16, Iss 4, Pp 85-94 (2013)
institution DOAJ
collection DOAJ
language EN
RU
topic diabetes mellitus
critical limb ischemia
percutaneous transluminal balloon angioplasty
tibial artery calcification
duplex ultrasonography
Nutritional diseases. Deficiency diseases
RC620-627
spellingShingle diabetes mellitus
critical limb ischemia
percutaneous transluminal balloon angioplasty
tibial artery calcification
duplex ultrasonography
Nutritional diseases. Deficiency diseases
RC620-627
Natalya Leonidovna Ayubova
Olga Nikolaevna Bondarenko
Gagik Radikovich Galstyan
Oksana Vladimirovna Manchenko
Ivan Ivanovich Dedov
Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease
description Aim. To assess the extent of the lower limb arterial calcification and to evaluate the long-term outcomes of percutaneous transluminal balloon angioplasty (PTBA) in patients with diabetes mellitus (DM), critical limb ischemia (CLI) and chronic kidney disease (CKD). Materials and Methods. 94 patients with CLI formed two groups (CKD-positive and CDK-negative). Quantitative assessment of tibial arterial calcification was performed with non-contrast CT. Outcomes of angioplasty were monitored during the 18?6 months of the follow-up period by means of duplex ultrasonography. Results.  Long-term outcomes of PTBA were significantly worse in patients with CKD. Nevertheless, limb preservation and survival rates were relatively satisfactory in both groups (74% and 72%, respectively). Conclusion. PTBA in patients with DM, CLI and CKD presents a technical challenge. Despite that, in many cases the endovascular intervention allows avoiding high-level amputations and improves survival rates.
format article
author Natalya Leonidovna Ayubova
Olga Nikolaevna Bondarenko
Gagik Radikovich Galstyan
Oksana Vladimirovna Manchenko
Ivan Ivanovich Dedov
author_facet Natalya Leonidovna Ayubova
Olga Nikolaevna Bondarenko
Gagik Radikovich Galstyan
Oksana Vladimirovna Manchenko
Ivan Ivanovich Dedov
author_sort Natalya Leonidovna Ayubova
title Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease
title_short Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease
title_full Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease
title_fullStr Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease
title_full_unstemmed Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease
title_sort clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease
publisher Endocrinology Research Centre
publishDate 2013
url https://doaj.org/article/7c5f174736214dfba9492d130072356e
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