Regulatory T cells confer a circadian signature on inflammatory arthritis

Circadian rhythms can alter inflammatory state and activity of inflammatory diseases such as rheumatoid arthritis. Here the authors show that extrinsic signals confer a circadian rhythm to regulatory T cell activity, which in turn drives rhythmic inflammation in collagen-induced arthritis.

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Detalles Bibliográficos
Autores principales:	L. E. Hand, K. J. Gray, S. H. Dickson, D. A. Simpkins, D. W. Ray, J. E. Konkel, M. R. Hepworth, J. E. Gibbs
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7c68db108e3949bb9e94ba02c45f7f2f
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spelling	oai:doaj.org-article:7c68db108e3949bb9e94ba02c45f7f2f2021-12-02T17:31:40ZRegulatory T cells confer a circadian signature on inflammatory arthritis10.1038/s41467-020-15525-02041-1723https://doaj.org/article/7c68db108e3949bb9e94ba02c45f7f2f2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15525-0https://doaj.org/toc/2041-1723Circadian rhythms can alter inflammatory state and activity of inflammatory diseases such as rheumatoid arthritis. Here the authors show that extrinsic signals confer a circadian rhythm to regulatory T cell activity, which in turn drives rhythmic inflammation in collagen-induced arthritis.L. E. HandK. J. GrayS. H. DicksonD. A. SimpkinsD. W. RayJ. E. KonkelM. R. HepworthJ. E. GibbsNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q L. E. Hand K. J. Gray S. H. Dickson D. A. Simpkins D. W. Ray J. E. Konkel M. R. Hepworth J. E. Gibbs Regulatory T cells confer a circadian signature on inflammatory arthritis
description	Circadian rhythms can alter inflammatory state and activity of inflammatory diseases such as rheumatoid arthritis. Here the authors show that extrinsic signals confer a circadian rhythm to regulatory T cell activity, which in turn drives rhythmic inflammation in collagen-induced arthritis.
format	article
author	L. E. Hand K. J. Gray S. H. Dickson D. A. Simpkins D. W. Ray J. E. Konkel M. R. Hepworth J. E. Gibbs
author_facet	L. E. Hand K. J. Gray S. H. Dickson D. A. Simpkins D. W. Ray J. E. Konkel M. R. Hepworth J. E. Gibbs
author_sort	L. E. Hand
title	Regulatory T cells confer a circadian signature on inflammatory arthritis
title_short	Regulatory T cells confer a circadian signature on inflammatory arthritis
title_full	Regulatory T cells confer a circadian signature on inflammatory arthritis
title_fullStr	Regulatory T cells confer a circadian signature on inflammatory arthritis
title_full_unstemmed	Regulatory T cells confer a circadian signature on inflammatory arthritis
title_sort	regulatory t cells confer a circadian signature on inflammatory arthritis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/7c68db108e3949bb9e94ba02c45f7f2f
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_version_	1718380562453889024

Regulatory T cells confer a circadian signature on inflammatory arthritis

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