Hydroxynonenal causes Langerhans cell degeneration in the pancreas of Japanese macaque monkeys.
<h4>Background</h4>For their functions of insulin biosynthesis and glucose- and fatty acid- mediated insulin secretion, Langerhans β-cells require an intracellular milieu rich in oxygen. This requirement makes β-cells, with their constitutively low antioxidative defense, susceptible to t...
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| Formato: | article |
| Lenguaje: | EN |
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Public Library of Science (PLoS)
2021
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| Acceso en línea: | https://doaj.org/article/7c6a5a6df7a94280899a449cbdafb5b0 |
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