The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis

Pathogenic bacteria of the genus Bartonella can induce vasoproliferative lesions during infection. Here, Tsukamoto et al. show that this effect is caused by a secreted protein that induces cell proliferation and angiogenesis by acting as an analog of the host’s vascular endothelial growth factor (VE...

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Autores principales:	Kentaro Tsukamoto, Naoaki Shinzawa, Akito Kawai, Masahiro Suzuki, Hiroyasu Kidoya, Nobuyuki Takakura, Hisateru Yamaguchi, Toshiki Kameyama, Hidehito Inagaki, Hiroki Kurahashi, Yasuhiko Horiguchi, Yohei Doi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7c6bada9dc8c434fa191c36a4398ea29
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spelling	oai:doaj.org-article:7c6bada9dc8c434fa191c36a4398ea292021-12-02T18:31:30ZThe Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis10.1038/s41467-020-17391-22041-1723https://doaj.org/article/7c6bada9dc8c434fa191c36a4398ea292020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17391-2https://doaj.org/toc/2041-1723Pathogenic bacteria of the genus Bartonella can induce vasoproliferative lesions during infection. Here, Tsukamoto et al. show that this effect is caused by a secreted protein that induces cell proliferation and angiogenesis by acting as an analog of the host’s vascular endothelial growth factor (VEGF).Kentaro TsukamotoNaoaki ShinzawaAkito KawaiMasahiro SuzukiHiroyasu KidoyaNobuyuki TakakuraHisateru YamaguchiToshiki KameyamaHidehito InagakiHiroki KurahashiYasuhiko HoriguchiYohei DoiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kentaro Tsukamoto Naoaki Shinzawa Akito Kawai Masahiro Suzuki Hiroyasu Kidoya Nobuyuki Takakura Hisateru Yamaguchi Toshiki Kameyama Hidehito Inagaki Hiroki Kurahashi Yasuhiko Horiguchi Yohei Doi The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis
description	Pathogenic bacteria of the genus Bartonella can induce vasoproliferative lesions during infection. Here, Tsukamoto et al. show that this effect is caused by a secreted protein that induces cell proliferation and angiogenesis by acting as an analog of the host’s vascular endothelial growth factor (VEGF).
format	article
author	Kentaro Tsukamoto Naoaki Shinzawa Akito Kawai Masahiro Suzuki Hiroyasu Kidoya Nobuyuki Takakura Hisateru Yamaguchi Toshiki Kameyama Hidehito Inagaki Hiroki Kurahashi Yasuhiko Horiguchi Yohei Doi
author_facet	Kentaro Tsukamoto Naoaki Shinzawa Akito Kawai Masahiro Suzuki Hiroyasu Kidoya Nobuyuki Takakura Hisateru Yamaguchi Toshiki Kameyama Hidehito Inagaki Hiroki Kurahashi Yasuhiko Horiguchi Yohei Doi
author_sort	Kentaro Tsukamoto
title	The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis
title_short	The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis
title_full	The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis
title_fullStr	The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis
title_full_unstemmed	The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis
title_sort	bartonella autotransporter bafa activates the host vegf pathway to drive angiogenesis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/7c6bada9dc8c434fa191c36a4398ea29
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The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis

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