Five-Years Angiographic Follow-Up of Wide-Neck Intracranial Aneurysms Treated With LEO Plus Stent

Background: This study aimed to evaluate the angiographic and clinical outcome, with an emphasis on long-term follow-up, of the LEO Plus stent for wide-neck intracranial aneurysms treated in a single center.Methods: We retrospectively examined a prospectively maintained database of patients treated...

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Autores principales: José M. Pumar, Paula Sucasas, Antonio Mosqueira, Pedro Vega, Eduardo Murias
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Publicado: Frontiers Media S.A. 2021
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spelling oai:doaj.org-article:7c76471252714b92a08d77cf6be15bcf2021-12-01T06:14:41ZFive-Years Angiographic Follow-Up of Wide-Neck Intracranial Aneurysms Treated With LEO Plus Stent1664-229510.3389/fneur.2021.744962https://doaj.org/article/7c76471252714b92a08d77cf6be15bcf2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fneur.2021.744962/fullhttps://doaj.org/toc/1664-2295Background: This study aimed to evaluate the angiographic and clinical outcome, with an emphasis on long-term follow-up, of the LEO Plus stent for wide-neck intracranial aneurysms treated in a single center.Methods: We retrospectively examined a prospectively maintained database of patients treated with LEO Plus devices between January 2004 and December 2016. Data regarding patient demographics, aneurysm characteristics, and technical procedures were analyzed. Angiographic and clinical findings were recorded during the procedure and followed up over a period of at least 5 years.Results: We identified 101 patients with 116 aneurysms. In 16 patients, the stent could not safely be placed. Thus, a total of 97 LEO Plus devices were implanted in 97 aneurysms of 85 patients. Adverse events (acute and delayed) were observed in 21.6% of cases (17/85), and most were resolved (70.6%; 12/17). Moreover, 5 years after the procedure, total morbidity and mortality were 2.3% (2/85) and 3.5% (3/85), respectively. Long-term imaging follow-up showed complete occlusions, neck remnants, and residual aneurysms in 73.1% (57/78), 14.1% (11/78), and 12.8% (10/78) of cases, respectively.Conclusions: Long-term results of treatment of brain aneurysms with LEO stent show high rates of adequate and stable occlusion over time, with acceptable morbidity and mortality.José M. PumarJosé M. PumarPaula SucasasPaula SucasasAntonio MosqueiraAntonio MosqueiraPedro VegaPedro VegaEduardo MuriasEduardo MuriasFrontiers Media S.A.articleaneurysmstenthemorrhageembolizationLEONeurology. Diseases of the nervous systemRC346-429ENFrontiers in Neurology, Vol 12 (2021)
institution DOAJ
collection DOAJ
language EN
topic aneurysm
stent
hemorrhage
embolization
LEO
Neurology. Diseases of the nervous system
RC346-429
spellingShingle aneurysm
stent
hemorrhage
embolization
LEO
Neurology. Diseases of the nervous system
RC346-429
José M. Pumar
José M. Pumar
Paula Sucasas
Paula Sucasas
Antonio Mosqueira
Antonio Mosqueira
Pedro Vega
Pedro Vega
Eduardo Murias
Eduardo Murias
Five-Years Angiographic Follow-Up of Wide-Neck Intracranial Aneurysms Treated With LEO Plus Stent
description Background: This study aimed to evaluate the angiographic and clinical outcome, with an emphasis on long-term follow-up, of the LEO Plus stent for wide-neck intracranial aneurysms treated in a single center.Methods: We retrospectively examined a prospectively maintained database of patients treated with LEO Plus devices between January 2004 and December 2016. Data regarding patient demographics, aneurysm characteristics, and technical procedures were analyzed. Angiographic and clinical findings were recorded during the procedure and followed up over a period of at least 5 years.Results: We identified 101 patients with 116 aneurysms. In 16 patients, the stent could not safely be placed. Thus, a total of 97 LEO Plus devices were implanted in 97 aneurysms of 85 patients. Adverse events (acute and delayed) were observed in 21.6% of cases (17/85), and most were resolved (70.6%; 12/17). Moreover, 5 years after the procedure, total morbidity and mortality were 2.3% (2/85) and 3.5% (3/85), respectively. Long-term imaging follow-up showed complete occlusions, neck remnants, and residual aneurysms in 73.1% (57/78), 14.1% (11/78), and 12.8% (10/78) of cases, respectively.Conclusions: Long-term results of treatment of brain aneurysms with LEO stent show high rates of adequate and stable occlusion over time, with acceptable morbidity and mortality.
format article
author José M. Pumar
José M. Pumar
Paula Sucasas
Paula Sucasas
Antonio Mosqueira
Antonio Mosqueira
Pedro Vega
Pedro Vega
Eduardo Murias
Eduardo Murias
author_facet José M. Pumar
José M. Pumar
Paula Sucasas
Paula Sucasas
Antonio Mosqueira
Antonio Mosqueira
Pedro Vega
Pedro Vega
Eduardo Murias
Eduardo Murias
author_sort José M. Pumar
title Five-Years Angiographic Follow-Up of Wide-Neck Intracranial Aneurysms Treated With LEO Plus Stent
title_short Five-Years Angiographic Follow-Up of Wide-Neck Intracranial Aneurysms Treated With LEO Plus Stent
title_full Five-Years Angiographic Follow-Up of Wide-Neck Intracranial Aneurysms Treated With LEO Plus Stent
title_fullStr Five-Years Angiographic Follow-Up of Wide-Neck Intracranial Aneurysms Treated With LEO Plus Stent
title_full_unstemmed Five-Years Angiographic Follow-Up of Wide-Neck Intracranial Aneurysms Treated With LEO Plus Stent
title_sort five-years angiographic follow-up of wide-neck intracranial aneurysms treated with leo plus stent
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/7c76471252714b92a08d77cf6be15bcf
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