Nrf2 activation does not affect adenoma development in a mouse model of colorectal cancer
Knatko et al. examined the importance of Nrf2 activity in the development of colorectal adenomas by performing genetic and pharmacological analyses. The authors found that Keap1 knockdown and Nrf2 activation impacted the metabolism of the non-tumoral colon, but did not affect colorectal adenoma form...
Guardado en:
Autores principales: | Elena V. Knatko, Cecilia Castro, Maureen Higgins, Ying Zhang, Tadashi Honda, Colin J. Henderson, C. Roland Wolf, Julian L. Griffin, Albena T. Dinkova-Kostova |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7c780740b0f74743a3772c55d2dbaca7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Molecular basis for the disruption of Keap1–Nrf2 interaction via Hinge & Latch mechanism
por: Yuta Horie, et al.
Publicado: (2021) -
Association of plasma C-reactive protein level with the prevalence of colorectal adenoma: the Colorectal Adenoma Study in Tokyo
por: Nano Kigawa, et al.
Publicado: (2017) -
Resting heart rate is associated with colorectal advanced adenoma.
por: Jihye Park, et al.
Publicado: (2021) -
Establishment and Verification of Scoring System for Colorectal Adenoma Recurrence
por: Xi X, et al.
Publicado: (2021) -
Paracrine cyclooxygenase-2 activity by macrophages drives colorectal adenoma progression in the Apc Min/+ mouse model of intestinal tumorigenesis
por: Mark A. Hull, et al.
Publicado: (2017)