Lessons Learned from <italic toggle="yes">In Vivo</italic> Studies of a Viral Noncoding RNA

ABSTRACT Despite increasing interest in the biology of noncoding RNAs (ncRNAs), few functions have been uncovered for viral ncRNAs in vivo. In their recent article in mSphere, Feldman and colleagues [E. R. Feldman et al., mSphere 1(2):e00105-15, 2016, doi:10.1128/mSphere.00105-15 ] demonstrate a hig...

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Autores principales: Rodney P. Kincaid, Christopher S. Sullivan
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
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Acceso en línea:https://doaj.org/article/7c83959472ab4e63b47792e92e780b7e
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Sumario:ABSTRACT Despite increasing interest in the biology of noncoding RNAs (ncRNAs), few functions have been uncovered for viral ncRNAs in vivo. In their recent article in mSphere, Feldman and colleagues [E. R. Feldman et al., mSphere 1(2):e00105-15, 2016, doi:10.1128/mSphere.00105-15 ] demonstrate a highly specific activity of a gammaherpesviral ncRNA in viral dissemination and establishment of latent infection. Their work highlights several interesting features that should be informative to future studies of viral ncRNA.