The RNA-binding protein ARPP21 controls dendritic branching by functionally opposing the miRNA it hosts

Many microRNA encoding regions are within introns of other coding genes, and yet the molecular or functional interaction between the two is unclear. This study shows that miR-128′s function is opposed by its host gene ARPP21, and they have complementary effects on neuronal development.

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Auteurs principaux: Frederick Rehfeld, Daniel Maticzka, Sabine Grosser, Pina Knauff, Murat Eravci, Imre Vida, Rolf Backofen, F. Gregory Wulczyn
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/7c8b8c16051e47579746c26c47d7c3ac
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