Alveolar bone loss and tooth loss are associated with COVID-19 severity but are not independent risk factors. An explorative study

Purpose: This study explores the association between alveolar bone loss, tooth loss and severity of COVID-19. Materials and methods: In this retrospective cohort study, we included patients with confirmed COVID-19 who have had a dental panoramic radiograph within a maximum period of 5 years, providi...

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Autores principales:	H.C.M. Donders, J.M. van der Sleen, Y.J. Kleinbergen, N. Su, J. de Lange, B.G. Loos
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	COVID19 Tooth loss Periodontitis Internal medicine RC31-1245 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/7c9d5e0927794718a8a5daa663285802
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spelling	oai:doaj.org-article:7c9d5e0927794718a8a5daa6632858022021-11-24T04:35:29ZAlveolar bone loss and tooth loss are associated with COVID-19 severity but are not independent risk factors. An explorative study2667-147610.1016/j.adoms.2021.100223https://doaj.org/article/7c9d5e0927794718a8a5daa6632858022022-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2667147621002120https://doaj.org/toc/2667-1476Purpose: This study explores the association between alveolar bone loss, tooth loss and severity of COVID-19. Materials and methods: In this retrospective cohort study, we included patients with confirmed COVID-19 who have had a dental panoramic radiograph within a maximum period of 5 years, providing information about alveolar bone loss and tooth loss. The severity of COVID-19 was determined based on the WHO clinical progression scale: (1) Mild/Ambulatory; (2) Moderate/Hospitalized; (3) Severe/Intensive care unit (ICU) or death. Results: 1730 patients were identified with COVID-19 from until October 31, 2020 in the Isala Hospital. Of these patients, 389 ever visited the OMFS department. 133 patients have had an orthopantomograph within a maximum period of 5 years and were included for analysis. The results showed a significant association between alveolar bone loss and COVID-19 severity (p = 0.028). Patients with alveolar bone loss had 5.6 times higher odds to be admitted to ICU or died, compared to ambulatory patients (OR: 5.60; 95%CI: 1.21; 25.99; P = 0.028). More tooth loss was significantly associated with COVID-19 severity (p = 0.047). Per tooth lost, patients had 4.2% higher odds for severe than mild COVID-19 (OR: 1.04; 95%CI: 1.00; 1.09; P = 0.047) and 6.0% higher odds for severe than moderate COVID-19 (OR: 1.06; 95%CI: 1.01; 1.11; P = 0.017). When adjusting for confounders in multivariate analyses, the significant associations of COVID-19 with alveolar bone loss and tooth loss were no longer present. Conclusion: In this retrospective explorative pilot study, alveolar bone loss and tooth loss are associated with the severity of COVID-19, however they are not independent risk factors. The current study could contribute to the design of further studies on the relationship between oral health and COVID-19.H.C.M. DondersJ.M. van der SleenY.J. KleinbergenN. SuJ. de LangeB.G. LoosElsevierarticleCOVID19Tooth lossPeriodontitisInternal medicineRC31-1245SurgeryRD1-811ENAdvances in Oral and Maxillofacial Surgery, Vol 5, Iss , Pp 100223- (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID19 Tooth loss Periodontitis Internal medicine RC31-1245 Surgery RD1-811
spellingShingle	COVID19 Tooth loss Periodontitis Internal medicine RC31-1245 Surgery RD1-811 H.C.M. Donders J.M. van der Sleen Y.J. Kleinbergen N. Su J. de Lange B.G. Loos Alveolar bone loss and tooth loss are associated with COVID-19 severity but are not independent risk factors. An explorative study
description	Purpose: This study explores the association between alveolar bone loss, tooth loss and severity of COVID-19. Materials and methods: In this retrospective cohort study, we included patients with confirmed COVID-19 who have had a dental panoramic radiograph within a maximum period of 5 years, providing information about alveolar bone loss and tooth loss. The severity of COVID-19 was determined based on the WHO clinical progression scale: (1) Mild/Ambulatory; (2) Moderate/Hospitalized; (3) Severe/Intensive care unit (ICU) or death. Results: 1730 patients were identified with COVID-19 from until October 31, 2020 in the Isala Hospital. Of these patients, 389 ever visited the OMFS department. 133 patients have had an orthopantomograph within a maximum period of 5 years and were included for analysis. The results showed a significant association between alveolar bone loss and COVID-19 severity (p = 0.028). Patients with alveolar bone loss had 5.6 times higher odds to be admitted to ICU or died, compared to ambulatory patients (OR: 5.60; 95%CI: 1.21; 25.99; P = 0.028). More tooth loss was significantly associated with COVID-19 severity (p = 0.047). Per tooth lost, patients had 4.2% higher odds for severe than mild COVID-19 (OR: 1.04; 95%CI: 1.00; 1.09; P = 0.047) and 6.0% higher odds for severe than moderate COVID-19 (OR: 1.06; 95%CI: 1.01; 1.11; P = 0.017). When adjusting for confounders in multivariate analyses, the significant associations of COVID-19 with alveolar bone loss and tooth loss were no longer present. Conclusion: In this retrospective explorative pilot study, alveolar bone loss and tooth loss are associated with the severity of COVID-19, however they are not independent risk factors. The current study could contribute to the design of further studies on the relationship between oral health and COVID-19.
format	article
author	H.C.M. Donders J.M. van der Sleen Y.J. Kleinbergen N. Su J. de Lange B.G. Loos
author_facet	H.C.M. Donders J.M. van der Sleen Y.J. Kleinbergen N. Su J. de Lange B.G. Loos
author_sort	H.C.M. Donders
title	Alveolar bone loss and tooth loss are associated with COVID-19 severity but are not independent risk factors. An explorative study
title_short	Alveolar bone loss and tooth loss are associated with COVID-19 severity but are not independent risk factors. An explorative study
title_full	Alveolar bone loss and tooth loss are associated with COVID-19 severity but are not independent risk factors. An explorative study
title_fullStr	Alveolar bone loss and tooth loss are associated with COVID-19 severity but are not independent risk factors. An explorative study
title_full_unstemmed	Alveolar bone loss and tooth loss are associated with COVID-19 severity but are not independent risk factors. An explorative study
title_sort	alveolar bone loss and tooth loss are associated with covid-19 severity but are not independent risk factors. an explorative study
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/7c9d5e0927794718a8a5daa663285802
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_version_	1718415920677781504

Alveolar bone loss and tooth loss are associated with COVID-19 severity but are not independent risk factors. An explorative study

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