Crystal structure of bacterial haem importer complex in the inward-facing conformation

Pathogenic bacteria acquire iron from heme cofactors imported by ABC heme transporters. Here the authors present crystal structures of Burkholderia cenocepaciaheme importer BhuUV with and without the heme-binding protein BhuT, gathering mechanistic insight into the catalytic cycle of heme import.

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Autores principales:	Youichi Naoe, Nozomi Nakamura, Akihiro Doi, Mia Sawabe, Hiro Nakamura, Yoshitsugu Shiro, Hiroshi Sugimoto
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7ca204fe49ee4f9494486ae36341efae
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spelling	oai:doaj.org-article:7ca204fe49ee4f9494486ae36341efae2021-12-02T14:38:57ZCrystal structure of bacterial haem importer complex in the inward-facing conformation10.1038/ncomms134112041-1723https://doaj.org/article/7ca204fe49ee4f9494486ae36341efae2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13411https://doaj.org/toc/2041-1723Pathogenic bacteria acquire iron from heme cofactors imported by ABC heme transporters. Here the authors present crystal structures of Burkholderia cenocepaciaheme importer BhuUV with and without the heme-binding protein BhuT, gathering mechanistic insight into the catalytic cycle of heme import.Youichi NaoeNozomi NakamuraAkihiro DoiMia SawabeHiro NakamuraYoshitsugu ShiroHiroshi SugimotoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Youichi Naoe Nozomi Nakamura Akihiro Doi Mia Sawabe Hiro Nakamura Yoshitsugu Shiro Hiroshi Sugimoto Crystal structure of bacterial haem importer complex in the inward-facing conformation
description	Pathogenic bacteria acquire iron from heme cofactors imported by ABC heme transporters. Here the authors present crystal structures of Burkholderia cenocepaciaheme importer BhuUV with and without the heme-binding protein BhuT, gathering mechanistic insight into the catalytic cycle of heme import.
format	article
author	Youichi Naoe Nozomi Nakamura Akihiro Doi Mia Sawabe Hiro Nakamura Yoshitsugu Shiro Hiroshi Sugimoto
author_facet	Youichi Naoe Nozomi Nakamura Akihiro Doi Mia Sawabe Hiro Nakamura Yoshitsugu Shiro Hiroshi Sugimoto
author_sort	Youichi Naoe
title	Crystal structure of bacterial haem importer complex in the inward-facing conformation
title_short	Crystal structure of bacterial haem importer complex in the inward-facing conformation
title_full	Crystal structure of bacterial haem importer complex in the inward-facing conformation
title_fullStr	Crystal structure of bacterial haem importer complex in the inward-facing conformation
title_full_unstemmed	Crystal structure of bacterial haem importer complex in the inward-facing conformation
title_sort	crystal structure of bacterial haem importer complex in the inward-facing conformation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/7ca204fe49ee4f9494486ae36341efae
work_keys_str_mv	AT youichinaoe crystalstructureofbacterialhaemimportercomplexintheinwardfacingconformation AT nozominakamura crystalstructureofbacterialhaemimportercomplexintheinwardfacingconformation AT akihirodoi crystalstructureofbacterialhaemimportercomplexintheinwardfacingconformation AT miasawabe crystalstructureofbacterialhaemimportercomplexintheinwardfacingconformation AT hironakamura crystalstructureofbacterialhaemimportercomplexintheinwardfacingconformation AT yoshitsugushiro crystalstructureofbacterialhaemimportercomplexintheinwardfacingconformation AT hiroshisugimoto crystalstructureofbacterialhaemimportercomplexintheinwardfacingconformation
_version_	1718390778586202112

Crystal structure of bacterial haem importer complex in the inward-facing conformation

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