Evaluation of Efficacy and Safety of All Pedicle Screw Posterior-Only Surgery in Patients with Dystrophic Neurofibromatosis Scoliosis

Background Data: Neurofibromatosis type 1 (NF-1) patients with dystrophic changes of the spine develop severe spinal deformity and/or instability and always need early surgical treatment. Combined anterior-posterior fusion was the treatment of choice of such curves because of the risk of progression...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autor principal:	Mohamed Serry ElSaeid AbdEllatif
Formato:	article
Lenguaje:	EN
Publicado:	Egyptian Spine Association 2019
Materias:	NF-1 dystrophic scoliosis posterior only surgery all pedicle screw deformity Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/7ca8277e31a1426cafe255774052a4cd
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:7ca8277e31a1426cafe255774052a4cd
record_format	dspace
spelling	oai:doaj.org-article:7ca8277e31a1426cafe255774052a4cd2021-12-02T03:04:41ZEvaluation of Efficacy and Safety of All Pedicle Screw Posterior-Only Surgery in Patients with Dystrophic Neurofibromatosis Scoliosis10.21608/esj.2019.6468.10832314-89502314-8969https://doaj.org/article/7ca8277e31a1426cafe255774052a4cd2019-01-01T00:00:00Zhttps://esj.journals.ekb.eg/article_30579.htmlhttps://doaj.org/toc/2314-8950https://doaj.org/toc/2314-8969Background Data: Neurofibromatosis type 1 (NF-1) patients with dystrophic changes of the spine develop severe spinal deformity and/or instability and always need early surgical treatment. Combined anterior-posterior fusion was the treatment of choice of such curves because of the risk of progression and pseudoarthrosis even in the presence of solid posterior fusion mass. Recent 3rd-generation posterior stabilization systems using pedicle screw fixation allow better 3-column purchase and 3D control and correction of deformity and stable posterior fixation of the spine preventing progression of the curves. Posterior-only surgery has been recently used in dystrophic NF-1 scoliosis due to use of pedicle screws fixation and development of different types of posterior release/osteotomies which lead to successful and sustained correction of these curves. Study Design: A retrospective clinical cohort study. Purpose: To study the results of posterior stabilization alone using all pedicle screws fixation in NF-1 patients with dystrophic scoliosis. Patients and Methods: 16 patients with NF-1 having dystrophic scoliosis were treated by posterior instrumentation using all pedicle screws. There were 5 female and 11 male patients and the average age was 13 years (range, 9–16 years). The study was done in the period between 2009 and 2016. Preoperative clinical examination included examination for neurofibromatosis, assessment of curve flexibility, and thorough neurological examination. Radiological examination included standard plain X-rays, anterior-posterior (A-P) and lateral and flexibility views, and MRI. Screw density of the whole construct and of the apical region (two vertebrae above and below the apex) was calculated. Functional outcomes were assessed by the ODI and SRS-30 scores at the last follow-up. Results: The mean follow-up was 5.15±1.78 years (range, 3–8). The mean Cobb angle improved in the coronal plane from 67.13±11.88 (range, 45–90◦) to 20±8.9 (range, 6–30◦) showing 70.1±11.2%. The mean preoperative sagittal plane deformity significantly improved from 61.82±20.28 (range, 35–90◦) to 25.91±7.68 (range, 10–35◦) postoperatively yielding 53.15±21.43 (range, 25–83.33%) mean correction with insignificant loss of correction at last follow-up. Loss of correction was 2±1.8% and 1.8±2.1% in the coronal and sagittal planes, respectively. At last follow-up the average SRS-30 score was 121±17.7 and the average ODI score was 8.46±3.26 without disability. Perioperative complications were minimal with no neurologic deficits, dural tears, or deep infection. Implant failure occurred in one patient. Conclusion: Our data suggest that posterior-only all pedicle screw based posterior instrumentation in NF-1 dystrophic scoliosis has been associated with good clinical outcome. It can be used safely in the presence of sufficient apical screw density (2018ESJ172). Mohamed Serry ElSaeid AbdEllatifEgyptian Spine AssociationarticleNF-1dystrophic scoliosisposterior only surgeryall pedicle screwdeformityNeurology. Diseases of the nervous systemRC346-429ENEgyptian Spine Journal, Vol 29, Iss 1, Pp 23-33 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	NF-1 dystrophic scoliosis posterior only surgery all pedicle screw deformity Neurology. Diseases of the nervous system RC346-429
spellingShingle	NF-1 dystrophic scoliosis posterior only surgery all pedicle screw deformity Neurology. Diseases of the nervous system RC346-429 Mohamed Serry ElSaeid AbdEllatif Evaluation of Efficacy and Safety of All Pedicle Screw Posterior-Only Surgery in Patients with Dystrophic Neurofibromatosis Scoliosis
description	Background Data: Neurofibromatosis type 1 (NF-1) patients with dystrophic changes of the spine develop severe spinal deformity and/or instability and always need early surgical treatment. Combined anterior-posterior fusion was the treatment of choice of such curves because of the risk of progression and pseudoarthrosis even in the presence of solid posterior fusion mass. Recent 3rd-generation posterior stabilization systems using pedicle screw fixation allow better 3-column purchase and 3D control and correction of deformity and stable posterior fixation of the spine preventing progression of the curves. Posterior-only surgery has been recently used in dystrophic NF-1 scoliosis due to use of pedicle screws fixation and development of different types of posterior release/osteotomies which lead to successful and sustained correction of these curves. Study Design: A retrospective clinical cohort study. Purpose: To study the results of posterior stabilization alone using all pedicle screws fixation in NF-1 patients with dystrophic scoliosis. Patients and Methods: 16 patients with NF-1 having dystrophic scoliosis were treated by posterior instrumentation using all pedicle screws. There were 5 female and 11 male patients and the average age was 13 years (range, 9–16 years). The study was done in the period between 2009 and 2016. Preoperative clinical examination included examination for neurofibromatosis, assessment of curve flexibility, and thorough neurological examination. Radiological examination included standard plain X-rays, anterior-posterior (A-P) and lateral and flexibility views, and MRI. Screw density of the whole construct and of the apical region (two vertebrae above and below the apex) was calculated. Functional outcomes were assessed by the ODI and SRS-30 scores at the last follow-up. Results: The mean follow-up was 5.15±1.78 years (range, 3–8). The mean Cobb angle improved in the coronal plane from 67.13±11.88 (range, 45–90◦) to 20±8.9 (range, 6–30◦) showing 70.1±11.2%. The mean preoperative sagittal plane deformity significantly improved from 61.82±20.28 (range, 35–90◦) to 25.91±7.68 (range, 10–35◦) postoperatively yielding 53.15±21.43 (range, 25–83.33%) mean correction with insignificant loss of correction at last follow-up. Loss of correction was 2±1.8% and 1.8±2.1% in the coronal and sagittal planes, respectively. At last follow-up the average SRS-30 score was 121±17.7 and the average ODI score was 8.46±3.26 without disability. Perioperative complications were minimal with no neurologic deficits, dural tears, or deep infection. Implant failure occurred in one patient. Conclusion: Our data suggest that posterior-only all pedicle screw based posterior instrumentation in NF-1 dystrophic scoliosis has been associated with good clinical outcome. It can be used safely in the presence of sufficient apical screw density (2018ESJ172).
format	article
author	Mohamed Serry ElSaeid AbdEllatif
author_facet	Mohamed Serry ElSaeid AbdEllatif
author_sort	Mohamed Serry ElSaeid AbdEllatif
title	Evaluation of Efficacy and Safety of All Pedicle Screw Posterior-Only Surgery in Patients with Dystrophic Neurofibromatosis Scoliosis
title_short	Evaluation of Efficacy and Safety of All Pedicle Screw Posterior-Only Surgery in Patients with Dystrophic Neurofibromatosis Scoliosis
title_full	Evaluation of Efficacy and Safety of All Pedicle Screw Posterior-Only Surgery in Patients with Dystrophic Neurofibromatosis Scoliosis
title_fullStr	Evaluation of Efficacy and Safety of All Pedicle Screw Posterior-Only Surgery in Patients with Dystrophic Neurofibromatosis Scoliosis
title_full_unstemmed	Evaluation of Efficacy and Safety of All Pedicle Screw Posterior-Only Surgery in Patients with Dystrophic Neurofibromatosis Scoliosis
title_sort	evaluation of efficacy and safety of all pedicle screw posterior-only surgery in patients with dystrophic neurofibromatosis scoliosis
publisher	Egyptian Spine Association
publishDate	2019
url	https://doaj.org/article/7ca8277e31a1426cafe255774052a4cd
work_keys_str_mv	AT mohamedserryelsaeidabdellatif evaluationofefficacyandsafetyofallpediclescrewposterioronlysurgeryinpatientswithdystrophicneurofibromatosisscoliosis
_version_	1718401991820967936

Evaluation of Efficacy and Safety of All Pedicle Screw Posterior-Only Surgery in Patients with Dystrophic Neurofibromatosis Scoliosis

Ejemplares similares