Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring

Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring

Extracellular vesicles (EVs) are present in circulation at relatively early stages of disease, providing potential opportunities for early cancer diagnosis. Here, the authors report a covalent chemistry-based hepatocellular carcinoma (HCC)-specific EV purification system for early detection of HCC b...

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Autores principales: Na Sun, Yi-Te Lee, Ryan Y. Zhang, Rueihung Kao, Pai-Chi Teng, Yingying Yang, Peng Yang, Jasmine J. Wang, Matthew Smalley, Pin-Jung Chen, Minhyung Kim, Shih-Jie Chou, Lirong Bao, Jing Wang, Xinyue Zhang, Dongping Qi, Juvelyn Palomique, Nicolas Nissen, Steven-Huy B. Han, Saeed Sadeghi, Richard S. Finn, Sammy Saab, Ronald W. Busuttil, Daniela Markovic, David Elashoff, Hsiao-hua Yu, Huiying Li, Anthony P. Heaney, Edwin Posadas, Sungyong You, Ju Dong Yang, Renjun Pei, Vatche G. Agopian, Hsian-Rong Tseng, Yazhen Zhu
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/7cae50dc76a9464fb0cb00c27a2f9b1f
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spelling oai:doaj.org-article:7cae50dc76a9464fb0cb00c27a2f9b1f2021-12-02T14:55:09ZPurification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring10.1038/s41467-020-18311-02041-1723https://doaj.org/article/7cae50dc76a9464fb0cb00c27a2f9b1f2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18311-0https://doaj.org/toc/2041-1723Extracellular vesicles (EVs) are present in circulation at relatively early stages of disease, providing potential opportunities for early cancer diagnosis. Here, the authors report a covalent chemistry-based hepatocellular carcinoma (HCC)-specific EV purification system for early detection of HCC by performing digital scoring on the purified EVs.Na SunYi-Te LeeRyan Y. ZhangRueihung KaoPai-Chi TengYingying YangPeng YangJasmine J. WangMatthew SmalleyPin-Jung ChenMinhyung KimShih-Jie ChouLirong BaoJing WangXinyue ZhangDongping QiJuvelyn PalomiqueNicolas NissenSteven-Huy B. HanSaeed SadeghiRichard S. FinnSammy SaabRonald W. BusuttilDaniela MarkovicDavid ElashoffHsiao-hua YuHuiying LiAnthony P. HeaneyEdwin PosadasSungyong YouJu Dong YangRenjun PeiVatche G. AgopianHsian-Rong TsengYazhen ZhuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Na Sun
Yi-Te Lee
Ryan Y. Zhang
Rueihung Kao
Pai-Chi Teng
Yingying Yang
Peng Yang
Jasmine J. Wang
Matthew Smalley
Pin-Jung Chen
Minhyung Kim
Shih-Jie Chou
Lirong Bao
Jing Wang
Xinyue Zhang
Dongping Qi
Juvelyn Palomique
Nicolas Nissen
Steven-Huy B. Han
Saeed Sadeghi
Richard S. Finn
Sammy Saab
Ronald W. Busuttil
Daniela Markovic
David Elashoff
Hsiao-hua Yu
Huiying Li
Anthony P. Heaney
Edwin Posadas
Sungyong You
Ju Dong Yang
Renjun Pei
Vatche G. Agopian
Hsian-Rong Tseng
Yazhen Zhu
Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring
description Extracellular vesicles (EVs) are present in circulation at relatively early stages of disease, providing potential opportunities for early cancer diagnosis. Here, the authors report a covalent chemistry-based hepatocellular carcinoma (HCC)-specific EV purification system for early detection of HCC by performing digital scoring on the purified EVs.
format article
author Na Sun
Yi-Te Lee
Ryan Y. Zhang
Rueihung Kao
Pai-Chi Teng
Yingying Yang
Peng Yang
Jasmine J. Wang
Matthew Smalley
Pin-Jung Chen
Minhyung Kim
Shih-Jie Chou
Lirong Bao
Jing Wang
Xinyue Zhang
Dongping Qi
Juvelyn Palomique
Nicolas Nissen
Steven-Huy B. Han
Saeed Sadeghi
Richard S. Finn
Sammy Saab
Ronald W. Busuttil
Daniela Markovic
David Elashoff
Hsiao-hua Yu
Huiying Li
Anthony P. Heaney
Edwin Posadas
Sungyong You
Ju Dong Yang
Renjun Pei
Vatche G. Agopian
Hsian-Rong Tseng
Yazhen Zhu
author_facet Na Sun
Yi-Te Lee
Ryan Y. Zhang
Rueihung Kao
Pai-Chi Teng
Yingying Yang
Peng Yang
Jasmine J. Wang
Matthew Smalley
Pin-Jung Chen
Minhyung Kim
Shih-Jie Chou
Lirong Bao
Jing Wang
Xinyue Zhang
Dongping Qi
Juvelyn Palomique
Nicolas Nissen
Steven-Huy B. Han
Saeed Sadeghi
Richard S. Finn
Sammy Saab
Ronald W. Busuttil
Daniela Markovic
David Elashoff
Hsiao-hua Yu
Huiying Li
Anthony P. Heaney
Edwin Posadas
Sungyong You
Ju Dong Yang
Renjun Pei
Vatche G. Agopian
Hsian-Rong Tseng
Yazhen Zhu
author_sort Na Sun
title Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring
title_short Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring
title_full Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring
title_fullStr Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring
title_full_unstemmed Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring
title_sort purification of hcc-specific extracellular vesicles on nanosubstrates for early hcc detection by digital scoring
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/7cae50dc76a9464fb0cb00c27a2f9b1f
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