The long history of a melanoma associated with a congenital large plaque type blue nevus with subcutaneous cellular nodules

The term large plaque type blue nevus with subcutaneous cellular nodules (LPTBN-SN) refers to a huge blue nevus, usually located on the trunk, that develops subcutaneous nodules many years after the lesion has appeared. The potential malignancy of an LPTBN-SN was only discovered in 2012. We repo...

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Autores principales:	Francesco Savoia, Giuseppe Gaddoni, Giuseppe Re, Emilia Crisanti
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2015
Materias:	blue nevus melanoma congenital large plaque type blue nevus with subcutaneous cellular nodules Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/7cb0f0142efb4e92bcfcb54ea8e02bb8
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spelling	oai:doaj.org-article:7cb0f0142efb4e92bcfcb54ea8e02bb82021-11-17T08:31:34ZThe long history of a melanoma associated with a congenital large plaque type blue nevus with subcutaneous cellular nodules10.5826/dpc.0503a042160-9381https://doaj.org/article/7cb0f0142efb4e92bcfcb54ea8e02bb82015-07-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/728https://doaj.org/toc/2160-9381 The term large plaque type blue nevus with subcutaneous cellular nodules (LPTBN-SN) refers to a huge blue nevus, usually located on the trunk, that develops subcutaneous nodules many years after the lesion has appeared. The potential malignancy of an LPTBN-SN was only discovered in 2012. We report the case of a 56-year-old Caucasian man that developed a cutaneous melanoma on an LPTBN-SN of the trunk. The first diagnosis was made more than 10 years before his death due to melanoma metastasis. The case reported here highlights the malignant potential of an LPTBN-SN, the very long course even without treatment and the possible coexistence of benign, borderline or malignant subcutaneous nodules in the same LPTBN-SN. Patients with large congenital blue nevi should be advised on the potential oncologic transformation of these lesions, the importance of follow-ups should be emphasized and, whenever possible, a preventive complete surgical removal should be evaluated before subcutaneous nodules develop. Francesco SavoiaGiuseppe GaddoniGiuseppe ReEmilia CrisantiMattioli1885articleblue nevusmelanomacongenitallarge plaque type blue nevus with subcutaneous cellular nodulesDermatologyRL1-803ENDermatology Practical & Conceptual (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	blue nevus melanoma congenital large plaque type blue nevus with subcutaneous cellular nodules Dermatology RL1-803
spellingShingle	blue nevus melanoma congenital large plaque type blue nevus with subcutaneous cellular nodules Dermatology RL1-803 Francesco Savoia Giuseppe Gaddoni Giuseppe Re Emilia Crisanti The long history of a melanoma associated with a congenital large plaque type blue nevus with subcutaneous cellular nodules
description	The term large plaque type blue nevus with subcutaneous cellular nodules (LPTBN-SN) refers to a huge blue nevus, usually located on the trunk, that develops subcutaneous nodules many years after the lesion has appeared. The potential malignancy of an LPTBN-SN was only discovered in 2012. We report the case of a 56-year-old Caucasian man that developed a cutaneous melanoma on an LPTBN-SN of the trunk. The first diagnosis was made more than 10 years before his death due to melanoma metastasis. The case reported here highlights the malignant potential of an LPTBN-SN, the very long course even without treatment and the possible coexistence of benign, borderline or malignant subcutaneous nodules in the same LPTBN-SN. Patients with large congenital blue nevi should be advised on the potential oncologic transformation of these lesions, the importance of follow-ups should be emphasized and, whenever possible, a preventive complete surgical removal should be evaluated before subcutaneous nodules develop.
format	article
author	Francesco Savoia Giuseppe Gaddoni Giuseppe Re Emilia Crisanti
author_facet	Francesco Savoia Giuseppe Gaddoni Giuseppe Re Emilia Crisanti
author_sort	Francesco Savoia
title	The long history of a melanoma associated with a congenital large plaque type blue nevus with subcutaneous cellular nodules
title_short	The long history of a melanoma associated with a congenital large plaque type blue nevus with subcutaneous cellular nodules
title_full	The long history of a melanoma associated with a congenital large plaque type blue nevus with subcutaneous cellular nodules
title_fullStr	The long history of a melanoma associated with a congenital large plaque type blue nevus with subcutaneous cellular nodules
title_full_unstemmed	The long history of a melanoma associated with a congenital large plaque type blue nevus with subcutaneous cellular nodules
title_sort	long history of a melanoma associated with a congenital large plaque type blue nevus with subcutaneous cellular nodules
publisher	Mattioli1885
publishDate	2015
url	https://doaj.org/article/7cb0f0142efb4e92bcfcb54ea8e02bb8
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The long history of a melanoma associated with a congenital large plaque type blue nevus with subcutaneous cellular nodules

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