Subdiffraction-Limited Quantum Imaging within a Living Cell
We report both subdiffraction-limited quantum metrology and quantum-enhanced spatial resolution for the first time in a biological context. Nanoparticles are tracked with quantum-correlated light as they diffuse through an extended region of a living cell in a quantum-enhanced photonic-force microsc...
Guardado en:
| Autores principales: | , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
American Physical Society
2014
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/7cbdee21ab144b84b8ce34580cb99e61 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:7cbdee21ab144b84b8ce34580cb99e61 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:7cbdee21ab144b84b8ce34580cb99e612021-12-02T11:29:23ZSubdiffraction-Limited Quantum Imaging within a Living Cell10.1103/PhysRevX.4.0110172160-3308https://doaj.org/article/7cbdee21ab144b84b8ce34580cb99e612014-02-01T00:00:00Zhttp://doi.org/10.1103/PhysRevX.4.011017http://doi.org/10.1103/PhysRevX.4.011017https://doaj.org/toc/2160-3308We report both subdiffraction-limited quantum metrology and quantum-enhanced spatial resolution for the first time in a biological context. Nanoparticles are tracked with quantum-correlated light as they diffuse through an extended region of a living cell in a quantum-enhanced photonic-force microscope. This allows spatial structure within the cell to be mapped at length scales down to 10 nm. Control experiments in water show a 14% resolution enhancement compared to experiments with coherent light. Our results confirm the long-standing prediction that quantum-correlated light can enhance spatial resolution at the nanoscale and in biology. Combined with state-of-the-art quantum light sources, this technique provides a path towards an order of magnitude improvement in resolution over similar classical imaging techniques.Michael A. TaylorJiri JanousekVincent DariaJoachim KnittelBoris HageHans-A. BachorWarwick P. BowenAmerican Physical SocietyarticlePhysicsQC1-999ENPhysical Review X, Vol 4, Iss 1, p 011017 (2014) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Physics QC1-999 |
| spellingShingle |
Physics QC1-999 Michael A. Taylor Jiri Janousek Vincent Daria Joachim Knittel Boris Hage Hans-A. Bachor Warwick P. Bowen Subdiffraction-Limited Quantum Imaging within a Living Cell |
| description |
We report both subdiffraction-limited quantum metrology and quantum-enhanced spatial resolution for the first time in a biological context. Nanoparticles are tracked with quantum-correlated light as they diffuse through an extended region of a living cell in a quantum-enhanced photonic-force microscope. This allows spatial structure within the cell to be mapped at length scales down to 10 nm. Control experiments in water show a 14% resolution enhancement compared to experiments with coherent light. Our results confirm the long-standing prediction that quantum-correlated light can enhance spatial resolution at the nanoscale and in biology. Combined with state-of-the-art quantum light sources, this technique provides a path towards an order of magnitude improvement in resolution over similar classical imaging techniques. |
| format |
article |
| author |
Michael A. Taylor Jiri Janousek Vincent Daria Joachim Knittel Boris Hage Hans-A. Bachor Warwick P. Bowen |
| author_facet |
Michael A. Taylor Jiri Janousek Vincent Daria Joachim Knittel Boris Hage Hans-A. Bachor Warwick P. Bowen |
| author_sort |
Michael A. Taylor |
| title |
Subdiffraction-Limited Quantum Imaging within a Living Cell |
| title_short |
Subdiffraction-Limited Quantum Imaging within a Living Cell |
| title_full |
Subdiffraction-Limited Quantum Imaging within a Living Cell |
| title_fullStr |
Subdiffraction-Limited Quantum Imaging within a Living Cell |
| title_full_unstemmed |
Subdiffraction-Limited Quantum Imaging within a Living Cell |
| title_sort |
subdiffraction-limited quantum imaging within a living cell |
| publisher |
American Physical Society |
| publishDate |
2014 |
| url |
https://doaj.org/article/7cbdee21ab144b84b8ce34580cb99e61 |
| work_keys_str_mv |
AT michaelataylor subdiffractionlimitedquantumimagingwithinalivingcell AT jirijanousek subdiffractionlimitedquantumimagingwithinalivingcell AT vincentdaria subdiffractionlimitedquantumimagingwithinalivingcell AT joachimknittel subdiffractionlimitedquantumimagingwithinalivingcell AT borishage subdiffractionlimitedquantumimagingwithinalivingcell AT hansabachor subdiffractionlimitedquantumimagingwithinalivingcell AT warwickpbowen subdiffractionlimitedquantumimagingwithinalivingcell |
| _version_ |
1718395887034564608 |