Interaction between mouse adenovirus type 1 and cell surface heparan sulfate proteoglycans.
Application of human adenovirus type 5 (Ad5) derived vectors for cancer gene therapy has been limited by the poor cell surface expression, on some tumor cell types, of the primary Ad5 receptor, the coxsackie-adenovirus-receptor (CAR), as well as the accumulation of Ad5 in the liver following interac...
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Auteurs principaux: | Liesbeth Lenaerts, Wim van Dam, Leentje Persoons, Lieve Naesens |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2012
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Accès en ligne: | https://doaj.org/article/7cc20047ec544fa9ab801ba14fdedf9a |
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