Single dose of multi-clade virus-like particle vaccine protects chickens against clade 2.3.2.1 and clade 2.3.4.4 highly pathogenic avian influenza viruses

Single dose of multi-clade virus-like particle vaccine protects chickens against clade 2.3.2.1 and clade 2.3.4.4 highly pathogenic avian influenza viruses

Abstract Virus-like particles (VLPs) are recognized as an alternative vaccine platform that provide effective protection against various highly pathogenic avian influenza viruses (HPAIVs). Here, we developed multi-clade VLPs expressing two HAs (a chimera of clade 2.3.2.1c and clade 2.3.4.4c HA) with...

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Main Authors: Yong-Myung Kang, Hyun-Kyu Cho, Ju Hun Kim, Su Jin Lee, Seo-Jeong Park, Do-Young Kim, Seong Yup Kim, Jung-won Park, Myoung-Heon Lee, Min-Chul Kim, Hyun-Mi Kang
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/7cc92c40f6c94ae3abae698aad48eac6
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