The Relationship Between Cognitive Dysfunction Through THINC-Integrated Tool (THINC-it) and Psychosocial Function in Chinese Patients With Major Depressive Disorder
Background: Herein, we validate the psychometric properties of the Chinese version of the THINC-integrated tool (THINC-it) as a screening tool for cognitive deficits in patients with major depressive disorder. The primary aim of this study is to determine whether cognitive deficits as detected by th...
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Frontiers Media S.A.
2021
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oai:doaj.org-article:7cca54e6c4df4752b2a817e410ee4a402021-11-30T13:12:23ZThe Relationship Between Cognitive Dysfunction Through THINC-Integrated Tool (THINC-it) and Psychosocial Function in Chinese Patients With Major Depressive Disorder1664-064010.3389/fpsyt.2021.763603https://doaj.org/article/7cca54e6c4df4752b2a817e410ee4a402021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fpsyt.2021.763603/fullhttps://doaj.org/toc/1664-0640Background: Herein, we validate the psychometric properties of the Chinese version of the THINC-integrated tool (THINC-it) as a screening tool for cognitive deficits in patients with major depressive disorder. The primary aim of this study is to determine whether cognitive deficits as detected by the THINC-it tool in adults with major depressive disorder (MDD) are associated with workplace productivity and/or psychosocial function.Methods: Subjects aged 18–65 (n = 91) with MDD were evaluated and compared to age-, sex- and education- matched healthy controls (n = 95). Symptoms of cognitive dysfunction, workplace productivity, and psychosocial function were measured using the THINC-it tool, Hamilton Depression Scale (HAMD), Sheehan Disability Scale (SDS), The Work Productivity and Activity Impairment questionnaire- Specific Health Problem (WPAI-SHP).Results: There were significant differences in THINC-it scores (p < 0.01), the average of HAMD total score (p < 0.01) and all aspects of SDS (p < 0.01) between two groups. There were significant differences in the four aspects of WPAI between the two groups in the employed status (p <0.01). THINC-it subjective cognition and SDS total score, SDS work/school, SDS social, SDS family showed significantly correlation (r ranging from 0.255 to 0.386, p <0.01). SDS and THINC-it Objective cognition, THINC-it comprehensive cognition were no correlation between two groups. HAMD total score and SDS total score, SDS social, SDS family showed significantly correlation (r rangingHan HanHan HanHan HanYanyan HouShuqiao YaoShaohua HuShaohua HuQi ZhouQi ZhouXin YuXin YuRoger S. McIntyreRoger S. McIntyreRoger S. McIntyreRoger S. McIntyreRoger S. McIntyreRoger S. McIntyreChuan ShiChuan ShiFrontiers Media S.A.articleMDDcognitive functionpsychosocial functionwork productivityTHINC-itPsychiatryRC435-571ENFrontiers in Psychiatry, Vol 12 (2021) |
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MDD cognitive function psychosocial function work productivity THINC-it Psychiatry RC435-571 |
| spellingShingle |
MDD cognitive function psychosocial function work productivity THINC-it Psychiatry RC435-571 Han Han Han Han Han Han Yanyan Hou Shuqiao Yao Shaohua Hu Shaohua Hu Qi Zhou Qi Zhou Xin Yu Xin Yu Roger S. McIntyre Roger S. McIntyre Roger S. McIntyre Roger S. McIntyre Roger S. McIntyre Roger S. McIntyre Chuan Shi Chuan Shi The Relationship Between Cognitive Dysfunction Through THINC-Integrated Tool (THINC-it) and Psychosocial Function in Chinese Patients With Major Depressive Disorder |
| description |
Background: Herein, we validate the psychometric properties of the Chinese version of the THINC-integrated tool (THINC-it) as a screening tool for cognitive deficits in patients with major depressive disorder. The primary aim of this study is to determine whether cognitive deficits as detected by the THINC-it tool in adults with major depressive disorder (MDD) are associated with workplace productivity and/or psychosocial function.Methods: Subjects aged 18–65 (n = 91) with MDD were evaluated and compared to age-, sex- and education- matched healthy controls (n = 95). Symptoms of cognitive dysfunction, workplace productivity, and psychosocial function were measured using the THINC-it tool, Hamilton Depression Scale (HAMD), Sheehan Disability Scale (SDS), The Work Productivity and Activity Impairment questionnaire- Specific Health Problem (WPAI-SHP).Results: There were significant differences in THINC-it scores (p < 0.01), the average of HAMD total score (p < 0.01) and all aspects of SDS (p < 0.01) between two groups. There were significant differences in the four aspects of WPAI between the two groups in the employed status (p <0.01). THINC-it subjective cognition and SDS total score, SDS work/school, SDS social, SDS family showed significantly correlation (r ranging from 0.255 to 0.386, p <0.01). SDS and THINC-it Objective cognition, THINC-it comprehensive cognition were no correlation between two groups. HAMD total score and SDS total score, SDS social, SDS family showed significantly correlation (r ranging |
| format |
article |
| author |
Han Han Han Han Han Han Yanyan Hou Shuqiao Yao Shaohua Hu Shaohua Hu Qi Zhou Qi Zhou Xin Yu Xin Yu Roger S. McIntyre Roger S. McIntyre Roger S. McIntyre Roger S. McIntyre Roger S. McIntyre Roger S. McIntyre Chuan Shi Chuan Shi |
| author_facet |
Han Han Han Han Han Han Yanyan Hou Shuqiao Yao Shaohua Hu Shaohua Hu Qi Zhou Qi Zhou Xin Yu Xin Yu Roger S. McIntyre Roger S. McIntyre Roger S. McIntyre Roger S. McIntyre Roger S. McIntyre Roger S. McIntyre Chuan Shi Chuan Shi |
| author_sort |
Han Han |
| title |
The Relationship Between Cognitive Dysfunction Through THINC-Integrated Tool (THINC-it) and Psychosocial Function in Chinese Patients With Major Depressive Disorder |
| title_short |
The Relationship Between Cognitive Dysfunction Through THINC-Integrated Tool (THINC-it) and Psychosocial Function in Chinese Patients With Major Depressive Disorder |
| title_full |
The Relationship Between Cognitive Dysfunction Through THINC-Integrated Tool (THINC-it) and Psychosocial Function in Chinese Patients With Major Depressive Disorder |
| title_fullStr |
The Relationship Between Cognitive Dysfunction Through THINC-Integrated Tool (THINC-it) and Psychosocial Function in Chinese Patients With Major Depressive Disorder |
| title_full_unstemmed |
The Relationship Between Cognitive Dysfunction Through THINC-Integrated Tool (THINC-it) and Psychosocial Function in Chinese Patients With Major Depressive Disorder |
| title_sort |
relationship between cognitive dysfunction through thinc-integrated tool (thinc-it) and psychosocial function in chinese patients with major depressive disorder |
| publisher |
Frontiers Media S.A. |
| publishDate |
2021 |
| url |
https://doaj.org/article/7cca54e6c4df4752b2a817e410ee4a40 |
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